Korean J Androl.  2006 Apr;24(1):13-17.

Vardenafil Improves Lower Urinary Tract Symptoms in Patients of Erectile Dysfunction

• Song SH
• Hong B
• You D
• Ahn TY

Abstract

PURPOSE: It is well known that male erectile dysfunction and lower urinary tract symptoms are common in aging men. We evaluated whether treatment for erectile dysfunction with vardenafil might improve lower urinary tract symptoms.
MATERIALS AND METHODS
From January 2004 to May 2005, 34 patients with erectile dysfunction attending the outpatient clinic were treated with vardenafil and followed up 1, 3, and 6 months after the treatment. They completed the International Index of Erectile Function (IIEF) and the International Prostate Symptom Score (IPSS) questionnaire at baseline and at each follow-up (1, 3, 6 months).
RESULTS
After treatment with vardenafil, IIEF and IPSS were significantly improved at 1 month compared to baseline,and the improvement was maintained during the 3 to 6 month follow-up period. There was no correlation between IPSS and IIEF score either before or after treatment. There was no statistical significance between the severity of IPSS and the response to vardenafil. There were mild side effects, including 2 patients with headache, 2 patients with facial flushing, and 1 patient with eye discomfort.
CONCLUSIONS
Vardenafil appears to improve not only erectile function but also lower urinary tract symptoms in men with erectile dysfunction. However, the severity of IPSS does not appear to predict the response to vardenafil therapy.

Keyword

Erectile dysfunction; Lower urinary tract symptoms; Vardenafil

MeSH Terms

Aging
Ambulatory Care Facilities
Erectile Dysfunction*
Flushing
Follow-Up Studies
Headache
Humans
Lower Urinary Tract Symptoms*
Male
Prostate
Vardenafil Dihydrochloride