J Korean Acad Fam Med.  2001 Nov;22(11):1630-1636.

Diabetes mellius and serum ferrtin concentration

• Han SH
• Lee SR
• Choi JH
• Yoo JH

Abstract

BACKGROUND: A prospective study about the association between serum ferritin concentration and diabetes mellitus showed that higher risk of diabetes was found in men in higher concentration of serum ferritin. The aims of this study is to examine the association between serum ferritin concentration and the risk of diabetes mellitus in healthy Korean in hospital-based samples.
METHODS
In a volunterred healthy population(n=14,782), who underwent health examination in Samsung Medical Center, from January to December 1997, serum ferritin and glucose were determined.
RESULTS
After adjusting for age, BMI, serum triglyceride concentration, and multiple logistic regression analysis showed that those in the highest quartile had increased risk of diabetes mellitus (OR: men 2.26(95% CI 2.41-2.95, p=0.0001), women 3.03(95% CI 2.51-3.67, p=0.0001), compared with those in the lowest quartile.
CONCLUSION
In studied population, elevated serum ferrtin concentration was associated with an increaed risk of diabetes.

Keyword

diabetes mellitus; serum ferritin; risk factor

MeSH Terms

Diabetes Mellitus
Female
Ferritins
Glucose
Humans
Logistic Models
Male
Prospective Studies
Risk Factors
Triglycerides
Ferritins
Glucose