Korean J Urol.
2004 Feb;45(2):181-184.
Primitive Neuroectodermal Tumor of the Kidney
- Affiliations
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- 1Department of Urology, Hanyang University College of Medicine, Seoul, Korea.
- 2Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.
Abstract
- Primitive neuroectodermal tumor (PNET), also referred to as extraskeletal Ewing's sarcoma, is a highly aggressive tumor, and it is seen typically in the soft tissues of the chest wall and paraspinal region but rarely arises in the kidney. A 27-year-old woman was presented with a left renal mass and underwent a radical nephrectomy. The pathological diagnosis was a primitive neuroectodermal tumor. Microscopically, there were sheets and lobules of cells with round to oval nuclei and coarse chromatin, as well as a Homer Wright rosette formation. Immunohistochemical analysis showed strongly positive staining of CD99 and negative staining of other neuroendocrine markers, such as synaptophysin and chromogranin.
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