Korean J Urol.  1985 Oct;26(5):549-551.

A Case of Kallmann's Syndrome

Affiliations
  • 1Department of Urology, School of Medicine, Kyung Hee University, Seoul, Korea.

Abstract

The association of anosmia with gonadal failure was first described by Kallmann et al. and reviewed by Nawakouski and Lenz. This hypogonadotropic hypogonadism is due to a defect of the hypothalamic level. We reported a case of Kallmann`s syndrome who was visited our department for evaluation of undescended testis. The patient was 15 year old male with anosmia and underdeveloped external genitalia. Hormonal study was done. On basal state. FSH was 1.1 mIU/ml, LH and testosterone were undetectable. 24 hours urine 17-OH CS is 4.5 mg/dl. After LH-RH 100 microgram was intravenous administration. LH value was 3.9mIU/ml. 2.0mIU/ml. 1.7mIU/ml. 1.0mIU/ml on 30', 60', 90', 120', respectively and FSH value was 3.8mIU/ml, 4.0mIU/ml, 4.9mIU/ml, 4.0mIU/ml on 30', 60', 90'. 120', respectively.

Keyword

Kallmann's syndrome

MeSH Terms

Administration, Intravenous
Adolescent
Cryptorchidism
Genitalia
Gonadotropin-Releasing Hormone
Gonads
Humans
Hypogonadism
Kallmann Syndrome*
Male
Olfaction Disorders
Testosterone
Gonadotropin-Releasing Hormone
Testosterone
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