Clinical Effect of Renal Angioinfarction in Renal Cell Carcinoma

Yu, Ji Ho; Park, Young Kyung

Abstract

Renal arterial embolization has been utilized in the treatment of renal tumor since Lalli and associates introduced angioinfarction of kidney in 1996. To determine whether preoperative infarction facilitated an operation in the patients with renal cell carcinoma we compared 5 patients that were managed by standard radical nephrectomy to 7 patients in that preoperative infarction and radical nephrectomy had been used. And we performed infarction in 2 patients of inoperable renal cancer for conservative primary management. After we had performed infarction of kidney in 3 dogs experimentally, a total of 9 patients with renal cell carcinoma underwent angioinfarction of kidney at our department of urology. Radical nephrectomy was performed in 7 of total 9 patients. Complete cessation of renal arterial flow could be demonstrated in all cases and subsequent surgical dissection was facilitated after angioinfarction. We concluded that renal angioinfarction reduce the volume and vascularity of the tumor and because the resulting edema sharpens the tissue planes, it makes surgical resection easy and it is also useful therapeutic method in the patients with renal cell carcinoma who were not surgical candidates.