- Favorable Immunotherapy Plus Tyrosine Kinase Inhibition Outcome of Renal Cell Carcinoma Patients with Low CDK5 Expression
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Xu X, Wang Y, Chen Z, Zhu Y, Wang J, Guo J
- KMID: 2547806
- Cancer Res Treat.
- 2023 Oct;55(4):1321-1336.
- doi: 10.4143/crt.2022.1532
Purpose Immunotherapy (IO) plus tyrosine kinase inhibitor (TKI) has become the first-line treatment for advanced renal cell carcinoma, despite the lack of prognostic biomarkers. Cyclin-dependent kinase 5 (CDK5) affects the... -
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- Technical Tips for Performing Suprahepatic Vena Cava Tumor Thrombectomy in Renal Cell Carcinoma without Using Cardiopulmonary Bypass
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Gwon JG, Cho YP, Han Y, Suh J, Min SK
- KMID: 2546637
- Vasc Spec Int.
- 2023 Sep;39(3):23.
- doi: 10.5758/vsi.230056
Radical nephrectomy with tumor thrombectomy for advanced renal cell carcinoma is an oncologically relevant approach that can achieve long-term survival even in the presence of distant metastases. However, the surgical... -
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- Cytoreductive nephrectomy in the age of immunotherapy-based combination treatment
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Song SH, Lee S
- KMID: 2545560
- Investig Clin Urol.
- 2023 Sep;64(5):425-434.
- doi: 10.4111/icu.20230187
Renal cell carcinoma (RCC) displays a wide spectrum of oncological prognosis and clinical behavior, and is noted for its generally poor outcome in metastatic settings. However, the introduction of immunotherapy... -
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- Efficacy of Partial Nephrectomy in the Management of Unpredicted pT3a Renal Cell Carcinoma
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Kim D, Lim B, Suh J, You D, Song C, Jeong IG, Hong B, Hong JH, Ahn H
- KMID: 2544865
- J Urol Oncol.
- 2023 Jul;21(2):148-153.
- doi: 10.22465/juo.224400400020
Purpose: To compare the oncological outcomes between patients with pathologic T3a (pT3a) renal cell carcinoma (RCC) who underwent partial nephrectomy (PN) and radical nephrectomy (RN). Materials and Methods: We retrospectively reviewed... -
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- Korean Urologic Oncology Society Guidelines: Does Angioembolization Improve the Quality of Life for Renal Cell Carcinoma Patients With Intractable Symptoms Who Are Unfit for Surgery?
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Ku JY, Gu HM, Yu SH, Hwang EC, Han MA, Jung JH, Lee H, Kim MH, Kwak C, Kim SI, for the Korean Urologic Oncology Society Guideline Development Committee, Korean Renal Cancer Study Group
- KMID: 2544864
- J Urol Oncol.
- 2023 Jul;21(2):140-147.
- doi: 10.22465/juo.234600180009
Purpose: There is a lack of guidelines for using angioembolization to manage renal cell carcinoma (RCC) patients with intractable symptoms. Therefore, the Korean Urologic Oncology Society (KUOS) developed a set... -
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- Loss of aquaporin-1 expression is associated with worse clinical outcomes in clear cell renal cell carcinoma: an immunohistochemical study
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Lee S, Kim B, Jung M, Moon KC
- KMID: 2544330
- J Pathol Transl Med.
- 2023 Jul;57(4):232-237.
- doi: 10.4132/jptm.2023.06.17
Background: Aquaporin (AQP) expression has been investigated in various malignant neoplasms, and the overexpression of AQP is related to poor prognosis in some malignancies. However, the expression of AQP protein... -
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- Melatonin acts synergistically with pazopanib against renal cell carcinoma cells through p38 mitogen-activated protein kinase-mediated mitochondrial and autophagic apoptosis
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Lai CP, Chen YS, Ying TH, Kao CY, Chiou HL, Kao SH, Hsieh YH
- KMID: 2547119
- Kidney Res Clin Pract.
- 2023 Jul;42(4):487-500.
- doi: 10.23876/j.krcp.22.114
Background: Mounting evidence indicates that melatonin has possible activity against different tumors. Pazopanib is an anticancer drug used to treat renal cell carcinoma (RCC). This study tested the anticancer activity... -
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- Bioinformatic analyses reveal the prognostic significance and potential role of ankyrin 3 (ANK3) in kidney renal clear cell carcinoma
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Somsuan K, Aluksanasuwan S
- KMID: 2543701
- Genomics Inform.
- 2023 Jun;21(2):e22.
- doi: 10.5808/gi.23013
Kidney renal clear cell carcinoma (KIRC) is one of the most aggressive cancer type of the urinary system. Metastatic KIRC patients have poor prognosis and limited therapeutic options. Ankyrin 3... -
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- Hereditary Leiomyomatosis and Renal Cell Cancer: A Case Report of Pilar Leiomyomatosis with History of Kidney Cancer and Review of the Literature
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Kim JW, Shin JW, Cho A, Huh CH
- KMID: 2542710
- Ann Dermatol.
- 2023 May;35(Suppl1):S14-S18.
- doi: 10.5021/ad.20.287
Pilar leiomyoma or piloleiomyoma is a benign neoplasm of the smooth muscle arising from the arrector pili muscle. It manifests as brown to red firm papulonodules with sites of predilection... -
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- The Prognostic Significance of Body Mass Index in Patients Undergoing Nephrectomy for Nonmetastatic Renal Cell Carcinoma
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- KMID: 2542209
- J Urol Oncol.
- 2023 Mar;21(1):88-94.
- doi: 10.22465/juo.224400480024
Purpose: The aim of this study was to evaluate the impact of body mass index (BMI) on survival in patients with nonmetastatic renal cell carcinoma (RCC) treated with radical or... -
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- Contemporary Management of Small Renal Masses by Urologic Oncologists: A 2022 Korean Renal Cancer Study Group Practice Pattern Survey
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- KMID: 2542206
- J Urol Oncol.
- 2023 Mar;21(1):59-69.
- doi: 10.22465/juo.234600120006
Purpose: Increased abdominal imaging brought about an explosive increase in the incidental detection of small renal masses (SRMs). In the absence of optimal guidelines for health screening, as well as... -
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- Superiority of magnetic resonance imaging in small renal mass diagnosis where image reports mismatches between computed tomography and magnetic resonance imaging
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Kim J, Lee JS, Jo Y, Han WK
- KMID: 2540061
- Investig Clin Urol.
- 2023 Mar;64(2):148-153.
- doi: 10.4111/icu.20220375
Purpose: To analyze malignancy of computed tomography (CT) and magnetic resonance imaging (MRI) results in the same renal mass. Materials and Methods: We retrospectively reviewed 1,216 patients who underwent partial nephrectomy... -
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- PD-L1 Upregulation by the mTOR Pathway in VEGFR-TKI–Resistant Metastatic Clear Cell Renal Cell Carcinoma
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Jeong SU, Hwang HS, Park JM, Yoon SY, Shin SJ, Go H, Lee JL, Jeong G, Cho YM
- KMID: 2538007
- Cancer Res Treat.
- 2023 Jan;55(1):231-244.
- doi: 10.4143/crt.2021.1526
Purpose Tyrosine kinase inhibitors (TKI) targeting vascular endothelial growth factor receptor (VEGFR) signaling pathways have been used for metastatic clear cell renal cell carcinoma (mCCRCC), but resistance to the drug... -
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- Current Trends in Liquid Biopsy Technology for Early Diagnosis of Metastatic Renal Cell Carcinoma
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Suh JY, Maeng SJ, Kim M, Kang SJ, Choi YW, Chang IH
- KMID: 2536651
- Korean J Urol Oncol.
- 2022 Nov;20(4):223-234.
- doi: 10.22465/kjuo.2022.20.4.223
Clear cell renal cell carcinoma (ccRCC) is a disease with a wide variety of clinical progressions such as the rate of disease progression or the degree of metastasis. About 30%... -
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- A retrospective single-centered, comprehensive targeted genetic sequencing analysis of prognostic survival using tissues from Korean patients with metastatic renal cell carcinoma after targeted therapy
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Kim SH, Park J, Park WS, Hong D, Chung J
- KMID: 2534615
- Investig Clin Urol.
- 2022 Nov;63(6):602-611.
- doi: 10.4111/icu.20210341
Purpose: To identify candidate gene mutations to significantly predict the risk of survival prognosis after treatment with systemic first-line targeted therapy (TT) in metastatic renal cell carcinoma (mRCC) patients. Materials and... -
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- 68Ga‑DOTATATE Avid Metastatic Vertebral Renal Cell Carcinoma in the Setting of von Hippel‑Lindau Syndrome
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Patel M, Jha A, Antic T, Nielsen S, Churpek J, Ling A, Pacak K
- KMID: 2534415
- Nucl Med Mol Imaging.
- 2022 Oct;56(5):259-562.
- doi: 10.1007/s13139-022-00761-7
Although rare, a metastatic renal cell carcinoma could present with 68Ga-DOTATATE avidity. A 66-year-old man with von Hippel-Lindau syndrome (VHL) presented with 68Ga-DOTATATE uptake in the pancreatic head, splenic hilar... -
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- Current and future perspectives on CAR-T cell therapy for renal cell carcinoma: A comprehensive review
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Kim TJ, Lee YH, Koo KC
- KMID: 2532882
- Investig Clin Urol.
- 2022 Sep;63(5):486-498.
- doi: 10.4111/icu.20220103
In the clinical setting of renal cell carcinoma (RCC), immune reactions such as tumor-specific T cell responses can be spontaneous events or can be elicited by checkpoint inhibitors, cytokines, and... -
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- 2021 Consensus Statements on the Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma From the Korean Renal Cancer Study Group (KRoCS)
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Lee CH, Kang M, Kwak C, Kim SH, Kim JK, Park JY, Seo SI, Seo IY, Suh J, Song W, Song C, Yuk HD, Lee S, Lee HH, Chung J, Jeong CW, Jo JK, Choi CI, Choo SH, Han JH, Hwang EC, Kim M, Kim C, Choi SH, Hong SH
- KMID: 2533086
- Korean J Urol Oncol.
- 2022 Aug;20(3):151-162.
- doi: 10.22465/kjuo.2022.20.3.151
Purpose: The Korean Renal Cancer Study Group (KRoCS) provides consensus recommendations on the role of cytoreductive nephrectomy (CRN) in patients with metastatic renal cell carcinoma (mRCC). Materials and Methods: A group... -
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- Is Cytoreductive Nephrectomy Still Beneficial for Patients With Metastatic Renal Cell Carcinoma in the Contemporary Immunotherapy Era?
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Choi JD, Cho JM, Yoo TK
- KMID: 2533085
- Korean J Urol Oncol.
- 2022 Aug;20(3):139-150.
- doi: 10.22465/kjuo.2022.20.3.139
Cytoreductive nephrectomy (CN) has long been the standard of care for patients with metastatic renal cell carcinoma (mRCC) since 2 clinical trials revealed its role during the cytokines era. With... -
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- Association between sarcopenia based on psoas muscle index and the response to nivolumab in metastatic renal cell carcinoma: A retrospective study
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Ueki H, Hara T, Okamura Y, Bando Y, Terakawa T, Furukawa J, Harada K, Nakano Y, Fujisawa M
- KMID: 2530910
- Investig Clin Urol.
- 2022 Jul;63(4):415-424.
- doi: 10.4111/icu.20220028
Purpose: Two methods are used to identify sarcopenia by calculating skeletal muscle area on computed tomography: the skeletal muscle index (SMI) and the psoas muscle index (PMI). Programmed death (PD)-1... -
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