J Asthma Allergy Clin Immunol.
2001 Dec;21(6):1211-1216.
A case of human toxocariasis with hypereosinophilic syndrome confirmed by serologic test
- Affiliations
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- 1Department of Allergy and Clinical Immunology, Ajou University, School of Medicine, Suwon, Korea. hspark@madang.ajou.ac.kr
- 2Department of Parasitology, Hallym University, College of Medicine, Chunchun, Korea.
Abstract
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Human toxocariasis is defined as the infection of a human host by the larval stages of Toxocara canis, a common intestinal parasite of dogs. We experienced a patient with hypereosinophilic syndrome involving liver and stomach caused by human toxocariasis. The diagnosis of toxocariasis was confirmed by detecting serum specific IgE antibody to Toxocara excretory-secretory antigens (TES-Ag) by ELISA and IgG immunoblot analysis, with high sensitivity and specificity for the diagnosis of toxocariasis. Toxocariasis should be considered one of the causative diseases inducing hypereosinophilic syndrome in this country.