J Asthma Allergy Clin Immunol.
2002 Sep;22(3):584-589.
Two cases of complete remission of aspirin-sensitive asthma
- Affiliations
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- 1Department of Allergy and Clinical Immunology, Ajou University, School of Medicine, Suwon, Korea. hspark@madang.ajou.ac.kr
Abstract
- Appreciable numbers of aspirin-sensitive asthmatic patients have chronic severe asthmatic symptoms. We report two cases of aspirin-sensitive asthmatics with mild asthmatic symptoms, whose methacholine PC20 levels were 9.07 and 7.06 mg/ml at first visit. The aspirin sensitivity was confirmed by lysine-aspirin bronchoprovocation at initial diagnosis. After anti-asthmatic medications and avoidance of salicylate-containing agents, respiratory symptoms, airway hyperrespon-siveness, and aspirin sensitivity disappeared after 33 and 45 months. These results suggest that early detection and careful avoidance of salicylate-containing agents may have beneficial effects resulting in resolution of airway hyperresponsiveness and aspirin sensitivity in aspirin-sensitive asthmatic patients.
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