Korean J Physiol Pharmacol.  2013 Aug;17(4):347-357. 10.4196/kjpp.2013.17.4.347.

A Review on Renal Toxicity Profile of Common Abusive Drugs

• Singh VP
• Singh N
• Jaggi AS

• KMID: 2285470
• DOI: http://doi.org/10.4196/kjpp.2013.17.4.347

Abstract

Drug abuse has become a major social problem of the modern world and majority of these abusive drugs or their metabolites are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal failure. The present review discusses the renal toxicity profile and possible mechanisms of commonly abused drugs including morphine, heroin, cocaine, nicotine, caffeine and alcohol.

Keyword

Caffeine; Cocaine; Heroin; Morphine; Renal failure

MeSH Terms

Caffeine
Cocaine
Heroin
Kidney
Kidney Failure, Chronic
Morphine
Nicotine
Renal Insufficiency
Social Problems
Substance-Related Disorders
Vascular Diseases
Caffeine
Cocaine
Heroin
Morphine
Nicotine

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