Intest Res.  2010 Dec;8(2):177-180. 10.5217/ir.2010.8.2.177.

A Pityrosporum Fungal Infection Following Infliximab Therapy in a Crohn's Disease Patient

Affiliations
  • 1Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea. skkim@mail.knu.ac.kr

Abstract

Crohn's disease (CD) is a chronic immune-mediated inflammatory disorder. Treatment strategies for CD are targeted toward various components of the proinflammatory mediators and subsequent immune response. Recently, the anti-tumor necrosis factor (TNF) monoclonal antibody, infliximab has been used in patients with CD. However, uncommon and unusual infections have been reported during anti-TNF-alpha therapy and immunomodulator. Here, we report a case of pityriasis versicolor occurring in a patient with CD receiving infliximab treatment. The patient was successfully treated with topical ketoconazole.

Keyword

Crohn Disease; Infliximab; Pityriasis Versicolor

MeSH Terms

Antibodies, Monoclonal
Crohn Disease
Humans
Infliximab
Ketoconazole
Malassezia
Necrosis
Tinea Versicolor
Antibodies, Monoclonal
Ketoconazole
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