Korean J Pediatr.  2012 Jun;55(6):202-205. 10.3345/kjp.2012.55.6.202.

Epidemiology of Kawasaki disease in infants 3 months of age and younger

• Lee EJ
• Park YW
• Hong YM
• Lee JS
• Han JW

• KMID: 2284490
• DOI: http://doi.org/10.3345/kjp.2012.55.6.202

Abstract

PURPOSE
This study investigated the epidemiology of Kawasaki disease (KD) in infants < or =3-month-old.
METHODS
To study the epidemiology of KD in Korea, data for 27,851 KD patients were collected on a 3-year basis between 2000 and 2008 in a retrospective survey. From this, data for 609 KD patients < or =3-month-old were analyzed and compared with the data for KD patients >3-month-old.
RESULTS
The 609 KD patients < or =3-month-old (385 males and 224 females) constituted 2.2% of the KD patients. They included 25 infants <1-month-old, 198 infants < or =1- to 2-month-old, and 386 infants >2- and 3-months-old. The ratio of males to females was 1.72:1. The incidence of coronary artery (CA) dilatation (19.9% vs. 18.7%) and CA aneurysms (3.4% vs. 2.6%) detected by echocardiography did not differ significantly between patients with KD younger and older than 3-month-old.
CONCLUSION
Compared with the data for the KD patients >3-month-old, the data for the 609 patients < or =3-month-old did not show a significantly higher incidence of CA dilatation or CA aneurysms.

Keyword

Kawasaki disease; Coronary artery dilatation; Coronary aneurysm; Epidemiology; Infant

MeSH Terms

Aneurysm
Coronary Aneurysm
Coronary Vessels
Dilatation
Echocardiography
Female
Humans
Incidence
Infant
Korea
Male
Mucocutaneous Lymph Node Syndrome
Retrospective Studies