Ewha Med J.  2009 Sep;32(2):85-89. 10.12771/emj.2009.32.2.85.

A Case of Lipiodol Pneumonitis After Transarterial Chemoembolization for Hepatocellular Carcinoma

• Kim SI
• Kim YR
• Heo HM
• Bae SE
• Lee MW
• Choi YJ
• Kim GH
• Kim TH
• Yoo K
• Moon IH

• KMID: 2283938
• DOI: http://doi.org/10.12771/emj.2009.32.2.85

Abstract

Hepatocellular carcinoma(HCC)is one of common causes of cancer-related death in Korea where the majority of HCC patients were Hepaitc B virus(HBV)carriers and have cirrhosis. Transarterial chemoembolization(TACE)is commonly applied to the treatment of multinodular HCC in Korea and careful selection of candidate is important for the risk of various side effects. Besides common side effects as fever, nausea, abdominal pain and elevation of liver enzyme, TACE may predispose to hepatic failure, ischemic cholecystitis, pulmonary embolism, cerebral embolism and pneumonitis. In previous studies, some cases of pulmonary and cerebral embolism cases were reported but lipiodol pneumonitis after TACE was rarely reported. A 65-year-old woman with a multinodular HCC associated with HBV infection, was treated with TACE. Seven days after the procedure, nonspecific respiratory symptoms such as dyspnea and dry cough developed. Chest X-ray and chest computed tomography showed diffuse ground glass opacities in whole lung fields, suggestive of lipiodol pneumonitis. After several days of supportive care with steroid administration, radiologic abnormalities and subjective symptoms were much improved, considered that the disease was compatible with lipiodol pneumonitis.

Keyword

Hepatocellular carcinoma; Transarterial chemoembolization; Lipiodol pneumonitis

MeSH Terms

Abdominal Pain
Aged
Carcinoma, Hepatocellular*
Cholecystitis
Cough
Dyspnea
Ethiodized Oil*
Female
Fever
Fibrosis
Glass
Humans
Intracranial Embolism
Korea
Liver
Liver Failure
Lung
Nausea
Pneumonia*
Pulmonary Embolism
Thorax
Ethiodized Oil