Ewha Med J.  2009 Sep;32(2):71-77. 10.12771/emj.2009.32.2.71.

Effect of Autogenous Iliac Bone Graft into the Loose Cancellous Bone Marrow On the Osseointegration in the Dog Tibia

• Kang NY
• Kim MR
• Kim SJ

• KMID: 2283936
• DOI: http://doi.org/10.12771/emj.2009.32.2.71

Abstract

OBJECTIVES
This study was performed to evaluate the effect of autogenous iliac particulated marrow cancellous bone graft on osseointegration of implants in the dog tibia which has a loose bone marrow.
METHODS
Three mongrel dogs, weighing about15kg or more, and RBM(resorbable blasted media) AVANA(R) implants(Osstem Inc., Korea) were used in this study. In the control groups, 2 implants sites were prepared conventionally with drills in the left metaphysic of tibia and 2 implants were placed in each dog under general anesthesia. In the experimental groups, 2 implant sites were prepared with drills. and the particulated marrow cancellous bone, which was obtained from the right ilium,was packed into both prepared sites with osteotomes in the right metaphysic of tib-ia in each dog. Two implants were placed. A total of 12 implants were placed in 3 dogs. The animals were sacrificed at 8 weeks after implant placement. The specimens were taken and embedded into the resin. H & E stain was done. The undecalcified specimens were prepared for histological examination and histomorphometric analysis of bone-implant contact ratios. The Mann-Whitney test was used to compare both groups.Values of p<0.01were considered statistically significant.
RESULTS
In the cross-sectional radiographs of the control group no trabecular bone was observed in the marrow space and the implant was surrounded with radiolucent marrow space. In the experimental group Some radioaque trabecular bone was observed in the marrow space of tibia and some of the trabecula was contacted with implant surface. Histologically,in the control group few trabecular bone was observed in marrow space and there was poor osseointegration in the marrow. In the experimental group most marrow space was filled with the trabecular boneand the implant surface was contacted with trabecular bone. In histomorphomeric analysis the bone-implant contact ratio of the experimental group(75.6%) was significantly higher than that of the control group(27.1%, p<0.01).
CONCLUSION
The autogeneous bone graft into the loose bone marrow can be an option to improve the bone density and to get better osseointegration of dental implants.

Keyword

PMCB(particulate marrow cancellous bone); Bone quality; Histomorphometry

MeSH Terms

Anesthesia, General
Animals
Bone Density
Bone Marrow*
Dental Implants
Dogs*
Metaphysics
Osseointegration*
Tibia*
Transplants*
Dental Implants