Korean J Pediatr.
2009 Jun;52(6):717-720. 10.3345/kjp.2009.52.6.717.
A case of newly developed pulmonary lesion during the antitubercular agents in tuberculous pleurisy : A paradoxical response
- Affiliations
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- 1Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea. cpr1@medigate.net
- 2Department of Pediatrics, Pochon CHA University, College of Medicine, Seoul, Korea.
- 3Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Konkuk University College of Medicine, Chungju, Chungbuk, Korea.
- 4Department of Radiology, Konkuk University College of Medicine, Chungju, Chungbuk, Korea.
- KMID: 2281080
- DOI: http://doi.org/10.3345/kjp.2009.52.6.717
Abstract
- Paradoxical response refers to the enlargement of old lesions or unexpected appearance of new lesions after initial improvement following treatment with antitubercular agents. Various types of paradoxical responses have been reported in the world, but they are rarely reported in Korean children. We report the case of a 17-year-old boy who was diagnosed with tuberculous pleurisy and was treated appropriately. Although the tuberculous pleurisy initially responded to medication with resolution of the pleural fluid, a new pulmonary lesion subsequently developed 3 weeks after the initiation of treatment that eventually cleared with continuation of the original drug regimen.
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