Korean J Pediatr.  2010 Nov;53(11):975-978. 10.3345/kjp.2010.53.11.975.

Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-alpha2b treatment

Affiliations
  • 1Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea. hoonkook@chonnam.ac.kr
  • 2Department of Pediatric Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea.
  • 3Department of Pathology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea.

Abstract

A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological examination revealed a low-grade perivascular epithelioid cell tumor (PEComa). PEComa in the colon is very rare. Only a few cases have been reported so far. An effective treatment method for this rare tumor has not been established yet. The patient received adjuvant interferon-alpha immunotherapy for 1 year. He has been tumor-free for 26 months since the initial diagnosis. This report is the first documented case of the use of interferon-alpha for pediatric PEComa of the colon.

Keyword

Perivascular epithelioid cell tumor; PEComa; Colon; Interferon-alpha

MeSH Terms

Abdominal Pain
Child
Colon
Colon, Ascending
Colonoscopy
Epithelioid Cells
Gastrointestinal Hemorrhage
Humans
Immunotherapy
Interferon-alpha
Perivascular Epithelioid Cell Neoplasms
Interferon-alpha
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