Korean J Pediatr.
2008 Nov;51(11):1228-1231. 10.3345/kjp.2008.51.11.1228.
A case of vancomycin-induced drug hypersensitivity syndrome
- Affiliations
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- 1Department of Pediatrics, Chonnam National University Medical School, Gwang-Ju, Korea. cardiol@jnu.ac.kr
- KMID: 2280249
- DOI: http://doi.org/10.3345/kjp.2008.51.11.1228
Abstract
- Drug hypersensitivity syndrome (DHS) has rarely been reported in association with vancomycin treatment. Here, we describe an 11-year-old girl who developed fever and a maculopapular rash on day 18 of intravenous vancomycin for treatment of infective endocarditis. The patient presented with fever, a maculopapular skin rash, hepatitis, and acute renal failure caused by vancomycin-induced DHS. The symptoms resolved in less than 24 h after withdrawal of vancomycin and treatment with corticosteroids. We present this case of DHS associated with vancomycin.
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