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Evaluation of copper alloys for reducing infection by methicillin resistant Staphylococcus aureus and vancomycin resistant Enterococcus faecium in intensive care unit and in vitro

Choi SI, Chang MS, Kim T, Chung KH, Bae S, Kim SH, Yoon CJ, Kim YK, Woo JH

Background/Aims: Multi-drug resistant pathogens are increasing among healthcare-associated infections. It is well known that copper and copper alloys have antimicrobial activity. We evaluated the activity of copper against bacteria in...
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Protective effects of lutein against vancomycin-induced acute renal injury in mice via upregulation of peroxisome proliferatoractivated receptor gamma/nuclear factor erythroid 2-related factor 2 and inhibition nuclear factor-kappaB/caspase 3

Emeka PM, Rasool ST, Morsy MA, Hairul Islam MI, Chohan MS

Vancomycin, an antibiotic used occasionally as a last line of treatment for methicillin-resistant Staphylococcus aureus, is reportedly associated with nephrotoxicity. This study aimed at evaluating the protective effects of lutein...
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It Is Time to Address the Isolation Policy for Patients Colonized with Vancomycin-resistant Enterococci

Chang E, Kim HB

Vancomycin-resistant enterococci (VRE) are one of the most important pathogens causing healthcare-associated infections. If VRE is detected in the culture tests of a patient’s clinical specimen, the patient should be...
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Optimizing the Dosing Regimens of Tigecycline against VancomycinResistant Enterococci in the Treatment of Intra-abdominal and Skin and Soft Tissue Infections

Santimaleeworagun W, Hemapanpairoa J, Changpradub D, Thunyaharn S

Tigecycline was previously considered to have activity against vancomycin-resistant Enterococcus (VRE) isolates, but the optimal dose was not clarified. Thus, this study assessed the in vitro activity of tigecycline against...
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A Meta-Analysis on the Performance of Cystatin C- versus Creatinine-based eGFR Equations in Predicting Vancomycin Clearance

Mohd Tahir NA, Saffian SM, Islahudin FH, Abdul Gafor AH, Makmor-Bakry M

Background: The objective of this study was to compare the performance of cystatin C- and creatinine-based estimated glomerular filtration rate (eGFR) equations in predicting the clearance of vancomycin. Methods: MEDLINE and...
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Transplantation of a kidney from a donor with vancomycin-resistant Enterococci

Lim JH, Kim CJ, Oh JH, Cho AY, Chang MO, Kim YS, Lee KY, Sun IO

The colonization of vancomycin-resistant Enterococci before and after solid organ transplantation is associated with an increased risk of its infection. The prevalence of these bacterial colonies in renal transplant recipients...
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Incidence of teicoplanin adverse drug reactions among patients with vancomycin-associated adverse drug reactions and its risk factors

Kim BK, Kim JH, Sohn KH, Kim JY, Chang YS, Kim SH

Background/Aims: Teicoplanin can be used as an alternative to vancomycin when treating beta-lactam-resistant gram-positive bacterial infections. Both vancomycin and teicoplanin are associated with relatively high rates of adverse drug reactions...
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Does oral doxycycline treatment affect eradication of urine vancomycin-resistant Enterococcus? A tertiary hospital study

Kim Y, Bae S, Hwang S, Kwon KT, Chang HH, Kim SJ, Park HK, Lee JM, Kim SW

Background: Vancomycin-resistant Enterococcus (VRE) has become more common in nosocomial infections, especially in urine samples. However, until now, no treatment regimen has been proven to effectively eradicate urine VRE colonization....
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Comparison of In Vivo Pharmacokinetics and Pharmacodynamics of Vancomycin Products Available in Korea

Kim HK, Choi SM, Kang G, Park KH, Lee DG, Park WB, Rhee SJ, Lee S, Jung SI, Jang HC

PURPOSE: Few studies have been investigated the in vivo efficacy of generic vancomycin products available outside of the United States. In this study, we aimed to compare the in vivo...
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Differences in Vancomycin Clearance between Trauma and Medical Intensive Care Unit Patients

Cho H, Lee S, Sheen S, Choi YH

Background: To identify the differences in the vancomycin pharmacokinetics between multiple trauma patients and medically ill patients in the intensive care unit (ICU) stratified by the use of continuous renal...
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Vancomycin and Aminoglycoside Antibiotic Drug Concentration Measurement: Current Status in Clinical Laboratories in Korea

Kwon WK, Oh J, Lee SY, Park HD

Background: Therapeutic drug monitoring (TDM) is clinically recommended for vancomycin and aminoglycoside antibiotics owing to their narrow therapeutic range and nephrotoxicity at high concentrations in the blood. This study was...
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Intraventricular Vancomycin Therapy for Intractable Bacillus cereus Ventriculitis

Hahn JW, Ju HY, Park M, Yi ES, Park BK, Shin SH, Lee SH, Park HJ, Kang JM

Bacillus cereus causes serious central nervous system infections, especially in immunocompromised patients. Successful treatment requires adequate antimicrobial concentrations in the cerebrospinal fluid; however, in some cases, achieving this with systemic...
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Comparison of the virulence of Streptococcus pneumoniae in ICR mouse stocks of three different origins

Kim JY, Seo SM, Lee HK, Kim HW, Choi YK

Streptococcus pneumoniae causes many people to suffer from pneumonia, septicemia, and other diseases worldwide. To identify the difference in susceptibility of and treatment efficacy against S. pneumoniae in three ICR...
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A Case of Vancomycin-induced Linear IgA Bullous Dermatosis

Choi W, Hahn HJ, Myung KB, Cheong SH

  • KMID: 2451597
  • Korean J Dermatol.
  • 2019 Jun;57(5):288-289.
No abstract available.
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In Situ Gelling Hydrogel with Anti-Bacterial Activity and Bone Healing Property for Treatment of Osteomyelitis

Jung SW, Oh SH, Lee IS, Byun JH, Lee JH

BACKGROUND: Despite the development of progressive surgical techniques and antibiotics, osteomyelitis is a big challenge for orthopedic surgeons. The main aim of this study is to fabricate an in situ...
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Shorter Incubation Times for Detecting Multi-drug Resistant Bacteria in Patient Samples: Defining Early Imaging Time Points Using Growth Kinetics and Total Laboratory Automation

Burckhardt I, Last K, Zimmermann S

BACKGROUND: The transition from manual processing of patient samples to automated workflows in medical microbiology is challenging. Although automation enables microbiologists to evaluate all samples following the same incubation period,...
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Preserved Efficacy of Oral Metronidazole for Severe Clostridium difficile Infection

Yu SN, Lee EJ

OBJECTIVE: Although clinical practice guidelines recommend oral vancomycin for hospitalized patients with severe Clostridium difficile infection (CDI), oral metronidazole is still the preferred regimen due to its tolerability and low...
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Intrawound Vancomycin Powder in Primary Total Hip Arthroplasty Increases Rate of Sterile Wound Complications

Dial BL, Lampley AJ, Green CL, Hallows R

PURPOSE: Total hip arthroplasty (THA) is a successful surgery for the treatment of hip osteoarthritis; however, the risk of a post-operative prosthetic joint infection (PJI) remains at 1% to 2%....
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In Vitro Study Evaluating the Antimicrobial Activity of Vancomycin-Impregnated Cement Stored at Room Temperature in Methicillin-Resistant Staphylococcus aureus

Park SJ, Cho Y, Lee SW, Woo HY, Lim SE

PURPOSE: Treatment of diabetic foot infection due to methicillin-resistant Staphylococcus aureus (MRSA) remains challenging. Applying vancomycin-impregnated cement is one of the best methods of treatment. Vancomycin-impregnated cement has been used...
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Antimicrobial therapy for methicillin-resistant Staphylococcus aureus

Choo EJ

Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of healthcare-associated infections. Recently, community-associated MRSA has emerged, manifesting as skin and soft tissue infections in patients without any prior healthcare contact....
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