Korean J Pediatr.  2008 Apr;51(4):401-408. 10.3345/kjp.2008.51.4.401.

Complications of transcatheter closure of atrial septal defects using the amplatzer septal occluder

• Jea SJ
• Kwon HJ
• Jang GY
• Lee JY
• Kim SJ
• Son CS
• Lee JW

• KMID: 2280160
• DOI: http://doi.org/10.3345/kjp.2008.51.4.401

Abstract

PURPOSE: Transcatheter closure of atrial septal defects (ASD) is currently established therapy as an alternative to surgery. But rarely, complications are reported in some studies. We report early and intermediate term complications associated with transcatheter closure of atrial septal defects using the Amplatzer septal occluder (ASO).
METHODS
From June 2003 to May 2006, 64 patients underwent transcatheter closure of secundum ASD or patent foramen ovale using the ASO. The ratio of male to female was 1:2.4, the median age was 17 years (range: 2.6-64 years) and their median weight was 47.5 kg (range: 2.6-64 kg).
RESULTS
The median diameter of ASD measured with transthoracic or transesophageal echocardiography was 15 mm (range: 6-28 mm), the median balloon stretched diameter was 18 mm (range: 6.5-34 mm), and the median size of device was 19.5 mm (range: 6-36 mm), was little difference with balloon stretched diameter. There were 10 cases of complications: arrhythmia (2), device malformation (2), aorta to right atrial fistula (1), hemolytic anemia (1), mitral valve encroachment (1), malposition (1), residual shunt (1), and inferior vena cava perforation (1).
CONCLUSION
Transcatheter closure of ASD using ASO is effective and safe therapy. However, significant complications such as aorta to atrial fistula, atrial erosion, or device embolization can happen, so an appropriate selection of patient and device in relevance to size and anatomy of ASD is important for successful closure.

Keyword

Atrial septal defect; Transcatheter closure; Complications

MeSH Terms

Anemia, Hemolytic
Aorta
Arrhythmias, Cardiac
Echocardiography, Transesophageal
Female
Fistula
Foramen Ovale, Patent
Heart Septal Defects, Atrial
Humans
Male
Mitral Valve
Septal Occluder Device
Vena Cava, Inferior