Korean J Pediatr Infect Dis.  2011 Jun;18(1):80-84.

Tuberculous Empyema Necessitatis with Osteomyelitis, a Rare Case in the 21st Century

Affiliations
  • 1Department of Pediatrics, School of Medicine, Ewha Womans University, Seoul, Korea. kaykim@ewha.ac.kr
  • 2Department of Thoracic and Cardiovascular Surgery, School of Medicine, Ewha Womans University, Seoul, Korea.
  • 3Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 4Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Empyema necessitatis refers to empyema that extends into the extrapleural space through a defect in the pleural surface. Tuberculous empyema necessitatis is a rare complication of tuberculosis. We experienced a 21-month-old boy with tuberculous empyema necessitatis with osteomyelitis in the right 7th rib. He presented with a mass on the right lateral chest wall, which was soft and nontender, enlarging for one month. He also had mild fever. The plain radiograph of his chest revealed soft tissue swelling and calcified lymph node on the left axilla, and his PPD skin test was positive. CT scan of the chest showed empyema necessitatis at the right lower chest and upper abdominal walls with osteomyelitis of the right 7th rib. He did not have concurrent pulmonary tuberculosis. Surgery was performed for diagnosis and treatment. In histopathologic findings, chronic granulomatous inflammation with caseation necrosis was shown and was positive for acid fast bacilli stain. In addition, M. tuberculosis complex was found as etiology by polymerase chain reaction. The patient has been treated with anti-tuberculous medication without any specific complication.

Keyword

Empyema; Pleural; Tuberculosis; Osteomyelitis

MeSH Terms

Axilla
Empyema
Empyema, Tuberculous
Fever
Humans
Infant
Inflammation
Lymph Nodes
Necrosis
Osteomyelitis
Polymerase Chain Reaction
Ribs
Skin Tests
Thoracic Wall
Thorax
Tuberculin
Tuberculosis
Tuberculosis, Pulmonary
Tuberculin

Reference

1. Jover F, Andreu L, Cuadrado J, Montaagud J, Merino J. Tuberculous empyema necessitatis in a man infected with the human immunodeficiency virus. South Med J. 2002. 95:751–752.
Article
2. Freeman AF, Ben-Ami T, Shulman ST. Streptococcus pneumoniae empyema necessitatis. Pediatr Infect Dis J. 2004. 23:177–179.
3. Moore FO, Berne JD, McGovern TM, Ravishankar S, Slamon NB, Hertzog JH. Empyema necessitatis in an infant: a rare surgical disease. J Pediatr Surg. 2006. 41:e5–e7.
Article
4. Baillou . Libri epidemiorum et ephemeridorum. 1640. Paris:
5. Sindel EA. Empyema necessitatis. Q Bull Sea View Hosp. 1940. 6:1–49.
6. Laënnec RTH. De l'auscultation médiate, ou, traité du diagnostique des maladies des poumons et du coeur: fondé principalement surce nouveau moyen d'exploration. 1819. Paris: Brossou et Chaudé.
7. Kono SA, Nauser TD. Contemporary empyema necessitatis. Am J Med. 2007. 120:303–305.
Article
8. Mehndiratta A, Lawande D, D'Costa L. Empyema necessitans following osteomyelitis of rib. Ind J Tub. 1999. 46:45–48.
9. Bishara J, Gartman-Israel D, Weinberger M, Maimon S, Tamir G, Pitlik S. Osteomyelitis of the ribs in the antibiotic era. Scand J Infect Dis. 2000. 32:223–227.
Article
10. Whalen JL, Fitzgerald RH Jr, Morrisy RT. A histological study of acute hematogenous osteomyelitis following physeal injuries in rabbits. J Bone Joint Surg Am. 1988. 70:1383–1392.
Article
11. Tonna I, Conlon CP, Davies RJ. A case of empyema necessitatis. Eur J Intern Med. 2007. 18:441–442.
Article
12. American Thoracic Society. CDC. Infectious Diseases Society of America. Treatment of Tuberculosis. MMWR Recomm Rep. 2003. 52:1–77.
13. Ludwig B, Lazarus AA. Musculoskeletal tuberculosis. Dis Mon. 2007. 53:39–45.
Article
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