Korean J Pediatr Infect Dis.  2009 Dec;16(2):210-214.

Group A beta-hemolytic Streptococcal Meningoencephalitis with Unilateral Hemiparesis

Affiliations
  • 1Department of Pediatrics and Adolescent Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea. jkchunped@yonsei.ac.kr
  • 2Department of Laboratory Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 3Department of Laboratory Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea.

Abstract

Group A streptococcus (GAS) rarely causes meningoencephalitis in children without risk factors. A previously healthy 8 year-old child presented with lethargy, high fever, and vomiting. The clinical course was unusual including intractable seizures, disseminated intravascular coagulation (DIC), and left hemiparesis in spite of the appropriate and timely administration of antibiotics and corticosteroids. The microbiologic studies revealed that the pathogen was susceptible to penicillin and GAS M18 strains. This case showed the importance of the GAS vaccine in addition to appropriate antibiotics.

Keyword

Invasive group A streptococcal infection; Coagulopathy; Hemiparesis; Children

MeSH Terms

Adrenal Cortex Hormones
Anti-Bacterial Agents
Child
Disseminated Intravascular Coagulation
Fever
Humans
Lethargy
Meningoencephalitis
Paresis
Penicillins
Risk Factors
Seizures
Streptococcus
Vomiting
Adrenal Cortex Hormones
Anti-Bacterial Agents
Penicillins
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