Korean J Pediatr.  2005 Feb;48(2):224-227.

A Case of Protein Losing Enteropathy Associated with Henoch-Schonlein Purpura

• Kim KD
• Oh CW
• Lee EY
• Kim JY

Abstract

Henoch-Schonlein purpura(HSP) is an IgA mediated immune complex vasculitic disease characterized by non-thrombocytic purpura, arthritis, gastrointestinal manifestations, and glomerulonephritis. HSP related glomerulonephritis induces hypoproteinemia and edema in some cases. Protein-losing enteropathy is another rare but known manifestation of HSP leading to hypoproteinemia and edema. We report a 6-year-old girl with HSP who showed edema caused by intestinal protein loss, evidenced by elevated fecal alpha 1 antitrypsin clearance.

Keyword

Henoch-Schonlein purpura; Protein losing enteropathy

MeSH Terms

alpha 1-Antitrypsin
Antigen-Antibody Complex
Arthritis
Child
Edema
Female
Glomerulonephritis
Humans
Hypoproteinemia
Immunoglobulin A
Protein-Losing Enteropathies*
Purpura
Purpura, Schoenlein-Henoch*
Antigen-Antibody Complex
Immunoglobulin A
alpha 1-Antitrypsin