Korean J Pediatr.  2006 Sep;49(9):991-995. 10.3345/kjp.2006.49.9.991.

A case of PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome

• Chae JH
• Hwang AR
• Park SH
• Suh BK

• KMID: 2278535
• DOI: http://doi.org/10.3345/kjp.2006.49.9.991

Abstract

PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome is one of the causes of periodic fever in pediatrics with unknown etiology. It is characterized by abrupt onset of fever, malaise, aphthous stomatitis, pharyngitis and cervical adenitis without long-term sequelae. Laboratory findings of this sporadic and nonhereditary syndrome are so non-specific that the diagnosis is based on clinical findings. Oral prednisolone is quite effective in controlling the symptoms. We report a case of a 6-year-old girl who was diagnosed as having PFAPA syndrome after 2 years of episodes, by excluding other disease entities with similar clinical features. The patient was treated with oral prednisolone and her symptoms improved dramatically.

Keyword

Periodic fever; Aphthous stomatitis; Pharyngitis; Cervical adenitis; Prednisolone

MeSH Terms

Child
Diagnosis
Female
Fever*
Humans
Lymphadenitis
Pediatrics
Pharyngitis*
Prednisolone
Stomatitis, Aphthous*
Yemen
Prednisolone