Korean J Pediatr.  2007 Jun;50(6):580-584. 10.3345/kjp.2007.50.6.580.

A case of childhood relapsing/remitting multiple sclerosis and interferon beta-1b treatment in a Korean patient

• Kim HS
• Lee WD
• Lee JH
• Cho KL

• KMID: 2278493
• DOI: http://doi.org/10.3345/kjp.2007.50.6.580

Abstract

Multiple sclerosis (MS) is a demyelinating disorder that affects discrete areas of the CNS, including the optic nerves, in a quite variable relapsing-remitting fashion over a prolonged period of time. Although MS is usually considered to be a disease that affects peoples in early to middle adulthood, children do develop multiple sclerosis. The frequency of MS onset before the age of 15 years is 2.7-5% of all cases, while MS onset during infancy and early childhood was observed to be 0.2- 0.7% of all cases. We report here on a Korean case of a relapsing-remitting MS female child who was treated with four rounds of intravenous methylpredinsolone pulse therapy and preventive Interferon-beta-1b (Betaferon(R)).

Keyword

Multiple Sclerosis, Optic neuritis, Interferon-beta-1b (Betaferon(R))

MeSH Terms

Child
Demyelinating Diseases
Female
Humans
Interferons*
Multiple Sclerosis*
Optic Nerve
Interferon beta-1b
Interferons