Korean J Pediatr.  2007 Jul;50(7):698-701. 10.3345/kjp.2007.50.7.698.

Two cases of Chryseobacterium meningosepticum infection in a neonatal intensive care unit

Affiliations
  • 1Department of Pediatrics, School of Medicine, Eulji University, Seoul, Korea. yhs3211@eulji.ac.kr

Abstract

We report on two premature infants who developed nosocomial infection caused by Chryseobacterium meningosepticum in a neonatal intensive care unit (NICU). One premature infant developed sepsis, meningitis, and hydrocephalus, and was treated successfully with ciprofloxacin plus trimethoprim-sulfamethoxazole combination therapy for 4 weeks and with a ventriculoperitoneal shunt. The other premature infant, who was in a chronically debilitated state, had infection that had colonized only in the respiratory tract but had no clinical signs for 66 days. Extensive environmental surveillance demonstrated that the suction bottle apparatus was the source of infection. We prevented the spread of infection by closing the NICU temporarily, isolating the patients early in their infection, and eradicating the source of infection source.

Keyword

Chryseobacterium meningosepticum; Ciprofloxacin; Neonatal intensive care unit

MeSH Terms

Chryseobacterium*
Ciprofloxacin
Colon
Cross Infection
Environmental Monitoring
Humans
Hydrocephalus
Infant, Newborn
Infant, Premature
Intensive Care, Neonatal*
Meningitis
Respiratory System
Sepsis
Suction
Trimethoprim, Sulfamethoxazole Drug Combination
Ventriculoperitoneal Shunt
Ciprofloxacin
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