Clin Exp Otorhinolaryngol.  2014 Jun;7(2):79-86.

Changing Patterns of Bacterial Strains in Adults and Children With Otitis Media in Korean Tertiary Care Centers

• Lee JS
• Kim MG
• Hong SM
• Na SY
• Byun JY
• Park MS
• Yeo SG

Abstract

OBJECTIVES
Otitis media (OM) is an infectious disease that affects all age brackets. Aural discharge is a typical symptom, occurring in all subtypes of OM. We have compared the identity and antibiotic sensitivity of bacteria isolated from aural discharges of adults and children with various types of OM, including acute OM (AOM), OM with effusion (OME), chronic OM (COM), and cholesteatomatous OM (CSOM).
METHODS
The study involved 2,833 patients who visited five tertiary hospitals between January 2001 and December 2010 and were diagnosed with AOM, OME, COM, or CSOM. The patients were divided into a pediatric group and an adult group, and the distribution of cultured bacteria and their antibiotic sensitivity were compared in the two groups.
RESULTS
Bacterial detection rates were higher in adults than in children with OME and COM (P=0.000 each). The majority of the bacteria cultured from patients with AOM and OME bacteria were methicillin-susceptible Staphylococcus aureus (MSSA) and Streptococcus pneumoniae. Bacteria cultured from children were more susceptible to antibiotics (P=0.002) and had higher antibiotic sensitivity (P=0.001) than were bacteria cultured from adults. The majority of bacteria culture from patients with COM and CSOM were MSSA and pathogenic Pseudomonas aeruginosa. The frequency of methicillin-resistant Staphylococcus aureus was significantly higher in adults than in children, and more strains of bacteria isolated from adults were sensitive to the antibiotics septrin, vancomycin, and teicoplanin.
CONCLUSION
Bacteria cultured from children were more susceptible to antibiotics and had higher antibiotic sensitivity than did bacteria cultured from adults.

Keyword

Otitis media; Bacteriology; Adult; Children

MeSH Terms

Adult*
Anti-Bacterial Agents
Bacteria
Bacteriology
Child*
Communicable Diseases
Humans
Methicillin-Resistant Staphylococcus aureus
Otitis Media*
Pseudomonas aeruginosa
Staphylococcus aureus
Streptococcus pneumoniae
Teicoplanin
Tertiary Care Centers*
Vancomycin
Trimethoprim, Sulfamethoxazole Drug Combination
Anti-Bacterial Agents
Teicoplanin
Vancomycin

Figure

• 

  Fig. 1 Changes in the rates of isolation of methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant Staphylococcus aureus (MRSA), and Pseudomonas aeruginosa (PA) in children (C) and adults (A) with otitis media from 2001 to 2010.

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