Korean J Pediatr Hematol Oncol.
1999 Oct;6(2):347-351.
Accidental Intrathecal Vincristine Administration
- Affiliations
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- 1Department of Pediatrics, Chungnam National University College of Medicine, Korea. kdpark@cnuh.co.kr
Abstract
- Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Accidental intrathecal vincristine instillation is a fatal error. We report a case of a 6-year-old boy with acute lymphocytic leukemia who suffered an accidental intrathecal vincristine administration. He suffered a progressive ascending chemical meningoencephalitis followed by coma, and died at the 5th day after injection. Several previous reports of intrathecal vincristine instillation are reviewed.
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