Korean J Pediatr Hematol Oncol.  1998 Apr;5(1):188-193.

A Case of Primary Cutaneous Aspergillosis in a Leukemic Child

• Choe JH
• Lee JH
• Lee KH
• Lee KC

Abstract

A 5-year-old boy developed painful erythematous indurated patch at vertex that rapidly progressed to central necrotic ulceration with peripheral granulation after chemotherapy for acute lymphoblastic leukemia. Cultures at the lesion sites demonstrated a fungus, Aspergillus niger, as the etiologic agent. No evidence of involvement of other organs or of systemic dissemination by Aspergillus niger was found. Surgical debridement was performed and the patient received treatment with intravenous Amphotericine B followed by oral itraconazole. No evidence of recurrent fungal infection was noted during several months of follow-up.

Keyword

Acute lymphoblastic leukemia; Aspergillus niger; Skin

MeSH Terms

Amphotericin B
Aspergillosis*
Aspergillus niger
Child*
Child, Preschool
Debridement
Drug Therapy
Follow-Up Studies
Fungi
Humans
Itraconazole
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Skin
Ulcer
Amphotericin B
Itraconazole