Korean J Otorhinolaryngol-Head Neck Surg.
2013 Jul;56(7):460-464. 10.3342/kjorl-hns.2013.56.7.460.
A Case of Bilateral Inverted Papilloma with Malignant Transformation on One Side: Analysis of the Expression of Tumor Related Genes on Each Side Tumors
- Affiliations
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- 1Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Chungnam National University, Daejeon, Korea. ksrha@cnu.ac.kr
- 2Research Institute for Medical Sciences, School of Medicine, Chungnam National University, Daejeon, Korea.
- KMID: 2277788
- DOI: http://doi.org/10.3342/kjorl-hns.2013.56.7.460
Abstract
- Inverted papillomas are relatively rare, benign tumors of the sinonasal cavity that generate interest to many clinicians because of their high rate of recurrences, locally invasive character and malignant transformation. The incidence of bilateral occurrence, ranging from 2 to 7%, is extremely rare, and the incidence of synchronous malignancy is also rare too. Here, we report an unusual case of bilateral inverted papilloma with a malignant transformation on one side. We compared the expression of molecules that suggested a relation with malignant transformation in inverted papilloma between each side of the tumors.
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