Korean J Otolaryngol-Head Neck Surg.  2006 Jun;49(6):666-668.

A Case of Vocal Cord Candidiasis

Affiliations
  • 1Departmet of Otolaryngology Head and Neck Surgery, Chonnam National University Medical School, Gwang-Ju, Korea. joonkyoo@jnu.ac.kr

Abstract

Candidal infection is recently reported to increase in certain predisposing condition, although isolated candidiasis from larynx is infrequently recognized and reported. Iisolated whitish lesions of vocal cord may be confused with precancerous lesions, squamous cell carcinoma, or verrucous carcinoma. A 62-year-old male visited our department for continuous hoarseness. Flexible laryngoscopy disclosed a whitish irregular exophytic mucosal lesion in right true vocal cord, which extended to anterior commissure and subglottis. Laryngeal microscopic surgery was done because of a concern regarding the possibility of glottic cancer. A pathologic biopsy revealed distorted and septated hypae and yeasts, scattered in moderate dysplasia. The patient was treated with itraconazole for 4 weeks, and followed up without any recurrence of candidiasis or dysplasia.

Keyword

Candidiasis; Larynx; Itraconazole

MeSH Terms

Biopsy
Candidiasis*
Carcinoma, Squamous Cell
Carcinoma, Verrucous
Hoarseness
Humans
Itraconazole
Laryngoscopy
Larynx
Male
Middle Aged
Recurrence
Vocal Cords*
Yeasts
Itraconazole
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