Korean J Pediatr Gastroenterol Nutr.  2011 Jun;14(2):181-186. 10.5223/kjpgn.2011.14.2.181.

A Case of Non-IgE-mediated Eosinophilic Gastroenteritis Presenting as Ascites

• Yi ES
• Kim MJ
• Ha SY
• Lee YM
• Choi KE
• Choe YH

• KMID: 2276539
• DOI: http://doi.org/10.5223/kjpgn.2011.14.2.181

Abstract

Eosinophilic gastroenteritis is a rare disease occurring especially in children, and shows various non-specific presentations with infiltration of eosinophils in the gastrointestinal organs. The pathophysiology of eosinophilic gastroenteritis is not yet clearly known, but allergic reactions are suspected to be related with the disease. Eosinophilic gastroenteritis is categorized into the mucosal, muscularis and subserosal types based on which layer of the intestinal wall is involved. There are different clinical manifestations according to the involved layer. Most cases to date have responded well to steroid therapy. In this study, we diagnosed and treated a case of non-IgE-mediated, subserosal eosinophilic gastroenteritis in a child with abdominal pain, diarrhea and ascites.

Keyword

Non-IgE-mediated; Eosinophilic gastroenteritis; Ascites

MeSH Terms

Abdominal Pain
Ascites
Child
Diarrhea
Enteritis
Eosinophilia
Eosinophils
Gastritis
Gastroenteritis
Humans
Hypersensitivity
Rare Diseases
Enteritis
Eosinophilia
Gastritis

Figure

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  Fig. 1 The ascitic fluid shows many eosinophils.

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  Fig. 2 Abdomen CT showed diffuse wall thickening of the small and large bowel.

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  Fig. 3 The endoscopic biopsy findings showed a marked eosinophil infiltration in the second portion of the duodenum (A) and the rectum (B) (H&E stain, 400).

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