Korean J Pathol.  2004 Jun;38(3):208-211.

Inflammatory Pseudotumor of the Paratesticular Area: A Case Report

Affiliations
  • 1Department of Pathology, Gachon Medical School Gil Medical Center, Incheon, Korea. jhhan@smc.samsung.co.kr
  • 2Department of Pathology, Sungkyunkwan University School of Medicine Samsung Medical Center, Seoul, Korea.

Abstract

Inflammatory pseudotumors of the paratesticular area are rare, and are often reported in the literature by various terms, e.g., proliferative funiculitis, inflammatory myofibroblastic tumor, pseudosarcomatous myofibroblastic proliferation and fibrous pseudotumor. This is one of the most common lesions of that region, and typically presents as a longstanding, painless scrotal mass. Here, we describe a 34 year-old man who has had a palpable scrotal mass for the past 10 years. The excised mass was composed of multiple conglomerated nodules, which had homogeneous rubbery cut surfaces. Histologically, each was a well circumscribed, but unencapsulated mass of hyalinized collagenous tissue interspersed with lymphoplasmacytic cells and lymphoid follicle formation. A small fraction of paucicellular spindle cells was positive for vimentin, smooth muscle actin and CD68. Ultrastructurally, abundant collagen fibrils were mixed with paucicellular spindle cells and inflammatory cells. These spindle cells had abundant rough endoplasmic reticula and myofilaments with focal densities, indicating myofibroblastic differentiation.

Keyword

Inflammatory pseudotumor; Paratesticular

MeSH Terms

Actins
Adult
Collagen
Granuloma, Plasma Cell*
Humans
Hyalin
Muscle, Smooth
Myofibrils
Myofibroblasts
Vimentin
Actins
Collagen
Vimentin
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