Korean J Pediatr Gastroenterol Nutr.
2008 Sep;11(2):204-209.
Nonalcoholic Fatty Liver Disease Progressing to Cirrhosis in an Obese Boy with Hypopituitarism
- Affiliations
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- 1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. jkseo@snu.ac.kr
- 2Department of Pediatrics, Konkuk University School of Medicine, Seoul, Korea.
- 3Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
- 4Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- Non-alcoholic fatty liver disease (NAFLD) is typically associated with obesity and insulin resistance. Non-alcoholic steatohepatitis (NASH) is a more serious form of NAFLD. Although fibrosis is common in pediatric NASH, cirrhosis has been rarely reported. Patients with hypothalamic or pituitary dysfunction are at risk for obesity and insulin resistance with subsequent development of NAFLD. We report a case of NAFLD progressing to cirrhosis in an obese 16 year-old boy with hypopituitarism.
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