Chonnam Med J.  2005 Aug;41(2):224-227.

A Case of Sigmoid Endometriosis Mimicking Colon Cancer

Affiliations
  • 1Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. sodium77@naver.com

Abstract

Endometriosis, the ectopic growth of endometrium, may occur in 8~15% of premenopausal women. Involvement of the gastrointestinal tract is relatively rare; but, the rectosigmoid colon is the most common site among the gastrointestinal involvement of ectopic endometriosis. Because the mucosa is infrequently involved, fluoroscopic and colonoscopic studies are usually negative. Therefore, differentiation between cancer and endometriosis of gastrointestinal tract is important to avoid unnecessary major operations. Here, we describe a case of 41-year-old woman with sigmoid endometriosis, in which the initial diagnostic work-up has been suggested colon cancer. On colonoscopy, erythematous nodular and irregular-surfaced lesion causing partial luminal obstruction was found at the rectosigmoid junction. Initial colonoscopic biopsy proved negative, but repeated colonoscopic biopsy performed one year later revealed endometrial glands surrounded by endometrial stromal cells in the lamina propria and muscularis mucosa, which led to the final diagnosis of ectopic endometriosis.

Keyword

Endometriosis; Colon cancer; Colonoscopy

MeSH Terms

Adult
Biopsy
Colon*
Colon, Sigmoid*
Colonic Neoplasms*
Colonoscopy
Diagnosis
Endometriosis*
Endometrium
Female
Gastrointestinal Tract
Humans
Mucous Membrane
Phenobarbital
Stromal Cells
Phenobarbital
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