Korean J Otolaryngol-Head Neck Surg.
1997 Nov;40(11):1675-1680.
A Case of Familial Medullary Thyroid Carcinoma
- Affiliations
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- 1Deptartment of Otolaryngology, School of Medicine, Ajou University, Suwon, Korea.
- 2Deptartment of Pathology, School of Medicine, Ajou University, Suwon, Korea.
Abstract
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Medullary thyroid carcinoma(MTC) is a malignancy of the thyroid C-cells, and it compromises 5-10% of all thyroid cancers. MTC occurs in both sporadic and hereditary types, the latter making up 25% of all MTCs and being compromised of three distinct syndromesmultiple endocrine neoplasia type IIa(MEN IIa), multiple endocrine neoplasia type IIb(MEN IIb), and familial medullary thyroid carcinoma(FMTC). To date, screening for MTC subtype is important for proper diagnosis and treatment. Recently, the authors experienced a case of FMTC. So, we report this case with the review of the literatures.