Korean J Obstet Gynecol.  2012 Nov;55(11):839-842. 10.5468/KJOG.2012.55.11.839.

Prenatal ultrasonographic diagnosis of congenital cataract: A case report

• Lee JO
• Lee JJ
• Kim MJ
• Lee HJ
• Lee DH
• Kim JS
• Park YK

• KMID: 2274153
• DOI: http://doi.org/10.5468/KJOG.2012.55.11.839

Abstract

Congenital cataracts are lens opacities that cause visual impairment in children. Early diagnosis of congenital cataracts is necessary because it facilitates appropriate intervention that can result in good visual function. Moreover, prenatal diagnosis, in particular, aids in the development of a therapeutic plan for the neonate. Ocular anomalies can be diagnosed prenatally because of the recent progress in obstetric ultrasonography. We report a case in which prenatal ultrasonography was used to diagnose congenital cataract. A brief review of the literature has also been provided.

Keyword

Congenital cataract; Prenatal; Obstetric ultrasonography

MeSH Terms

Cataract
Child
Early Diagnosis
Humans
Infant, Newborn
Prenatal Diagnosis
Ultrasonography, Prenatal
Vision Disorders

Figure

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  Fig. 1 (A) Ultrasonographic coronal view of the fetal right eye at 28 weeks and 4 days of gestation shows a hyperechoic lens. (B) Ultrasonographic axial view of the fetal left eye at 28 weeks and 4 days of gestation shows a hyperechoic lens.

Reference

1. Monteagudo A, Timor-Tritsch IE, Friedman AH, Santos R. Autosomal dominant cataracts of the fetus: early detection by transvaginal ultrasound. Ultrasound Obstet Gynecol. 1996. 8:104–108.

2. Cengiz B, Baxi L. Congenital cataract in triplet pregnancy after ivf with frozen embryos: prenatal diagnosis and management. Fetal Diagn Ther. 2001. 16:234–236.

3. Lambert SR, Lynn MJ, Reeves R, Plager DA, Buckley EG, Wilson ME. Is there a latent period for the treatment of children with dense bilateral cataracts? J AAPOS. 2006. 10:30–36.

4. Burgess IA, Martin SL, Hines BA, Smith JE. Prenatal detection of congenital idiopathic cataracts. Med J Aust. 1998. 169:385–386.

5. Scott MH, Hejtmancik JF, Wozencraft LA, Reuter LM, Parks MM, Kaiser-Kupfer MI. Autosomal dominant congenital cataract. Interocular phenotypic variability. Ophthalmology. 1994. 101:866–871.

6. Gaary EA, Rawnsley E, Marin-Padilla JM, Morse CL, Crow HC. In utero detection of fetal cataracts. J Ultrasound Med. 1993. 12:234–236.

7. Cotlier E. Congenital varicella cataract. Am J Ophthalmol. 1978. 86:627–629.

8. Pearce WG. Ocular and genetic features of Cockayne's syndrome. Can J Ophthalmol. 1972. 7:435–444.

9. Mashiach R, Vardimon D, Kaplan B, Shalev J, Meizner I. Early sonographic detection of recurrent fetal eye anomalies. Ultrasound Obstet Gynecol. 2004. 24:640–643.

10. Başbuğ M, Serin IS, Ozçelik B, Guneş T, Akçakuş M, Tayyar M. Prenatal ultrasonographic diagnosis of rhizomelic chondrodysplasia punctata by detection of rhizomelic shortening and bilateral cataracts. Fetal Diagn Ther. 2005. 20:171–174.

11. Reches A, Yaron Y, Burdon K, Crystal-Shalit O, Kidron D, Malcov M, et al. Prenatal detection of congenital bilateral cataract leading to the diagnosis of Nance-Horan syndrome in the extended family. Prenat Diagn. 2007. 27:662–664.

12. Daskalakis G, Anastasakis E, Lyberopoulos E, Antsaklis A. Prenatal detection of congenital cataract in a fetus with Lowe syndrome. J Obstet Gynaecol. 2010. 30:409–410.

13. Jo EJ, Kwak HM, Ji HY, Cha HH, Choi SJ, Oh SY, et al. A case report: prenatal diagnosis of idiopathic congenital cataract. Korean J Ultrasound Obstet Gynecol. 2011. 13:73–76.

14. Birch EE, Stager DR. The critical period for surgical treatment of dense congenital unilateral cataract. Invest Ophthalmol Vis Sci. 1996. 37:1532–1538.

15. Zimmer EZ, Bronshtein M, Ophir E, Meizner I, Auslender R, Groisman G, et al. Sonographic diagnosis of fetal congenital cataracts. Prenat Diagn. 1993. 13:503–511.