J Korean Ophthalmol Soc.  1996 Apr;37(4):708-712.

A Case of Congenital Cataract in Down's Syndrome

• Shin DS
• Ahn SK
• Koo BS

Abstract

In most cases of chromosomal anomaly of congenital cataract, the cause is known as Down's syndrome. We experienced a case of bilateral congenital cataract in Trisomy 21 (Down's syndrome). A 3 year-old female who had been born from 37 year-old mother was visited to our hospital, with clinical diagnosis of bilateral congenital cataract. Her face was pathognomonic to Down's syndrome. Chromosomal study of peripheral blood showed that the total number of chromosome was 47, and karyotype was 47, XX, +21. The lens showed nuclear opacity. Aspiration and Discission of the cataract on both eyes were performed uneventfully.

Keyword

Congenital cataract; Down's syndrome

MeSH Terms

Adult
Cataract*
Child, Preschool
Diagnosis
Down Syndrome*
Female
Humans
Karyotype
Mothers