Korean J Obstet Gynecol.  2006 Dec;49(12):2473-2478.

Ovarian tissue cryopreservation and transplantation

Affiliations
  • 1Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea. kh8730@yumc.yonsei.ac.kr

Abstract

This review focuses on the current options for fertility preservation in patients with high risk of premature ovarian failure. Available cryopreservation options include embryo cryopreservation, oocyte cryopreservation, and ovarian tissue cryopreservation. Ovarian tissue cryopreservation and transplantation has been tried for some time in animals, but only recently successful pregnancy and livebirth in human has been reported. Options of developing follicles and restoring fertility after ovarian tissue cryopreservation are autotransplantation, xenotransplantation, and tissue culture. This review discusses the merits and faults of each option and future directions for developing and standardizing the ovarian tissue cryopreservation and transplantation procedure, systemically covering previously published data.

Keyword

Fertility preservation; Ovarian tissue cryopreservation and transplantation

MeSH Terms

Animals
Autografts
Cryopreservation*
Embryonic Structures
Fertility
Fertility Preservation
Humans
Oocytes
Pregnancy
Primary Ovarian Insufficiency
Transplantation, Heterologous
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