Korean J Obstet Gynecol.  2005 Sep;48(9):2157-2165.

The clinical efficacy of body mass index as a predictor of in vitro fertilization and embryo transfer outcomes

• Kim SD
• Jee BC
• Ku SY
• Suh CS
• Choi YM
• Kim JG
• Moon SY
• Kim SH

Abstract

OBJECTIVE
To evaluate the clinical efficacy of body mass index (BMI) as a predictor of in vitro fertilization and embryo transfer (IVF-ET) outcomes.
METHODS
Two hundred twenty-three IVF-ET cycles in 164 patients under 37 years using GnRH agonist long protocol were included in this retrospective study. All of the selected cases were divided into two groups by BMI of 24 kg/m2 and these two groups were compared in regard to the outcomes of IVF-ET.
RESULTS
There were no significant differences between Group 1 (BMI<24 kg/m2) and Group 2 (BMI> or =24 kg/m2) in age, basal serum FSH level, estradiol (E2) level and endometrial thickness on hCG day, number of retrieved oocytes and transferred embryos. However, more gonadotropins were used in Group 2 with borderline significance (30.8+/-12.7 ampules vs. 35.4+/-15.3 ampules, p=0.051). The clinical pregnancy rate was significantly lower in Group 2 (25.9% vs. 10.5%, p=0.041) and implantation rate tended to be lower in Group 2 with borderline significance (12.7% vs. 6.8%, p=0.085).
CONCLUSION
BMI> or =24 kg/m2 may have a detrimental effect on the IVF-ET outcomes in Korean infertile women, and BMI may be a candidate predictor for IVF outcomes.

Keyword

Body mass index (BMI); In vitro fertilization and embryo transfer (IVF-ET); Pregnancy; Prediction

MeSH Terms

Body Mass Index*
Embryo Transfer*
Embryonic Structures*
Estradiol
Female
Fertilization in Vitro*
Gonadotropin-Releasing Hormone
Gonadotropins
Humans
Oocytes
Pregnancy
Pregnancy Rate
Retrospective Studies
Estradiol
Gonadotropin-Releasing Hormone
Gonadotropins