- Intelectin-1 and Endocrinological Parameters in Women with Polycystic Ovary Syndrome: Effect of Insulin Resistance
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Al-Fartosy AJM, Awad NA, Mohammed A
- KMID: 2468838
- Ewha Med J.
- 2020 Jan;43(1):1-11.
- doi: 10.12771/emj.2020.43.1.1
OBJECTIVES: We aimed to evaluate the effect of insulin resistance (IR) on serum Intelectin-1 and endocrinological hormones levels in obese and non-obese women with and without polycystic ovary syndrome (PCOS)... -
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- Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review
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Riazi H, Ghazanfarpour M, Taebi M, Abdolahian S
- KMID: 2466825
- J Menopausal Med.
- 2019 Dec;25(3):109-116.
- doi: 10.6118/jmm.19194
Menopause is associated with the onset of climacteric symptoms due to low estradiol levels, which may cause insufficient maturation of the vaginal mucosa. Vitamin D may regulate the growth and... -
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- The Effect of Trigonella foenum-graceum L. (Fenugreek) Towards Collagen Type I Alpha 1 (COL1A1) and Collagen Type III Alpha 1 (COL3A1) on Postmenopausal Woman's Fibroblast
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Yusharyahya SN, Bramono K, Sutanto NR, Kusuma I
- KMID: 2459961
- Nat Prod Sci.
- 2019 Sep;25(3):208-214.
- doi: 10.20307/nps.2019.25.3.208
Trigonella foenum-graceum L. (fenugreek) is a phytoestrogen, a nonsteroidal organic chemical compound from plants which has similar mechanism of action to sex hormone estradiol-17β. This study aims to assess the... -
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- Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice
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Lee J, Lee HC, Kim SY, Cho GJ, Woodruff T
- KMID: 2450407
- Yonsei Med J.
- 2019 Jul;60(7):667-678.
- doi: 10.3349/ymj.2019.60.7.667
PURPOSE: The aim of this study was to investigate how type I diabetes mellitus (T1D) affects the folliculogenesis and oocyte development, fertilization, and embryo development. MATERIALS AND METHODS: A comparative animal... -
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- Effect of Estradiol in an Azoxymethane/Dextran Sulfate Sodium-Treated Mouse Model of Colorectal Cancer: Implication for Sex Difference in Colorectal Cancer Development
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Son HJ, Sohn SH, Kim N, Lee HN, Lee SM, Nam RH, Park JH, Song CH, Shin E, Na HY, Kim JS, Lee DH, Surh YJ
- KMID: 2464410
- Cancer Res Treat.
- 2019 Apr;51(2):632-648.
- doi: 10.4143/crt.2018.060
PURPOSE: This study demonstrates that estradiol downregulates inflammation and inhibits colorectal cancer (CRC) development in azoxymethane/dextran sulfate sodium (AOM/DSS) mouse model. MATERIALS AND METHODS: AOM/DSS-treated male and female mice were sacrificed... -
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- The Effects of Menopausal Hormone Therapy on Serum Level of C-reactive Protein in Postmenopausal Korean Women
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Shin W, Kim SE, Lee JY, Seo JW, Hyun HS, Suh JH, Choi D, Yoon BK
- KMID: 2443627
- J Menopausal Med.
- 2019 Apr;25(1):49-54.
- doi: 10.6118/jmm.2019.25.1.49
OBJECTIVES: Inflammation is a major mechanism underlying coronary heart disease (CHD) and C-reactive protein (CRP) is a marker of inflammation. When administered soon after menopause, menopausal hormone therapy (MHT) prevents... -
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- Prevalence of CYP17A1 gene mutations in 17α-hydroxylase deficiency in the Chinese Han population
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Wang M, Wang H, Zhao H, Li L, Liu M, Liu F, Meng F, Fan C
- KMID: 2468629
- Clin Hypertens.
- 2019 ;25(1):23.
- doi: 10.1186/s40885-019-0128-6
BACKGROUND: 17α-hydroxylase deficiency is a rare autosomal recessive disorder caused by mutations in the cytochrome P450 family 17 subfamily A member 1 gene. The major clinical presentation includes hypertension, hypokalemia,... -
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- Estrogen-secreting adrenocortical carcinoma
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Jeong Y, Cho SC, Cho HJ, Song JS, Kong JS, Park JW, Ku YH
- KMID: 2434100
- Yeungnam Univ J Med.
- 2019 Jan;36(1):54-58.
- doi: 10.12701/yujm.2019.00017
Adrenocortical carcinoma is a rare type of endocrine malignancy with an annual incidence of approximately 1–2 cases per million. The majority of these tumors secrete cortisol, and a few secrete... -
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- Age of Postmenopause Women: Effect of Soy Isoflavone in Lipoprotein and Inflammation Markers
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Barrasa GR, González Cañete N, Boasi LE
- KMID: 2455891
- J Menopausal Med.
- 2018 Dec;24(3):176-182.
- doi: 10.6118/jmm.2018.24.3.176
OBJECTIVES: Menopause is associated with adverse metabolic changes in plasma lipoprotein and inflammation markers. Estrogens have beneficial effects on lipid metabolism and inflammation. Isoflavones (ISO) have structurally similar to estradiol.... -
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- The effect of Puerariae Radix on ovariectomy-induced bone loss in C3H/HeN mice
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Ahn B, Lee S, Kang S, Moon C, Kim JC, Jang JS, Kim SH
- KMID: 2435742
- J Biomed Transl Res.
- 2018 Dec;19(4):73-78.
- doi: 10.12729/jbtr.2018.19.4.073
Osteoporosis is a major worldwide public health problem that poses a great economic burden to society. Puerariae Radix, the dried root of Pueraria lobata (Wild.) Ohwi, has been widely used... -
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- Protective effects of saffron against zearalenone-induced alterations in reproductive hormones in female mice (Mus musculus)
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Ahmad B, Shrivastava VK, Saleh R, Henkel R, Agarwal A
- KMID: 2427411
- Clin Exp Reprod Med.
- 2018 Dec;45(4):163-169.
- doi: 10.5653/cerm.2018.45.4.163
OBJECTIVE: Zearalenone (ZEA) is a mycotoxin with potent estrogenic effects. Saffron is an herbal product that has antioxidant activities. The objective of this study was to investigate the protective role... -
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- Sex hormones alter the response of Toll-like receptor 3 to its specific ligand in fallopian tube epithelial cells
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Zandieh Z, Amjadi F, Vakilian H, Aflatoonian K, Amirchaghmaghi E, Fazeli A, Aflatoonian R
- KMID: 2427410
- Clin Exp Reprod Med.
- 2018 Dec;45(4):154-162.
- doi: 10.5653/cerm.2018.45.4.154
OBJECTIVE: The fallopian tubes play a critical role in the early events of fertilization. The rapid innate immune defense is an important part of the fallopian tubes. Toll-like receptor 3... -
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- Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model
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Song CH, Kim N, Sohn SH, Lee SM, Nam RH, Na HY, Lee DH, Surh YJ
- KMID: 2427459
- Gut Liver.
- 2018 Nov;12(6):682-693.
- doi: 10.5009/gnl18221
BACKGROUND/AIMS: Intestinal barrier dysfunction is a hallmark of inflammatory bowel diseases (IBDs) such as ulcerative colitis. This dysfunction is caused by increased permeability and the loss of tight junctions in... -
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- Estrogen reinforces barrier formation and protects against tumor necrosis factor alpha-induced barrier dysfunction in oral epithelial cells
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Choi YS, Baek K, Choi Y
- KMID: 2424862
- J Periodontal Implant Sci.
- 2018 Oct;48(5):284-294.
- doi: 10.5051/jpis.2018.48.5.284
PURPOSE: Epithelial barrier dysfunction is involved in the pathophysiology of periodontitis and oral lichen planus. Estrogens have been shown to enhance the physical barrier function of intestinal and esophageal epithelia,... -
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- Ginkgo biloba extract (EGb761) did not express estrogenic activity in an immature rat uterotrophic assay
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Moon B, Kim W, Park CH, Oh SM
- KMID: 2434041
- Environ Health Toxicol.
- 2018 Sep;33(3):e2018016.
- doi: 10.5620/eht.e2018016
Ginkgo biloba is a dioecious tree that has been used in traditional Chinese medicine for about 5,000 years. In previous studies on Ginkgo biloba extract (EGb761) using in vitro systems,... -
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- High Estradiol Differentially Affects the Expression of the Glucose Transporter Type 4 in Pelvic Floor Muscles of Rats
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de los Ãngeles Carrasco-Ruiz , Hernández-Aragón LG, Chávez-RÃos JR, RodrÃguez-AntolÃn J, Pacheco P, MartÃnez-Gómez M, Cuevas-Romero E, Castelán
- KMID: 2422503
- Int Neurourol J.
- 2018 Sep;22(3):161-168.
- doi: 10.5213/inj.1836116.058
PURPOSE: To characterize the relationship between serum estradiol levels and the expression of glucose transporter type 4 (Glut4) in the pubococcygeus and iliococcygeus muscles in female rats. METHODS: The muscles were... -
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- The influence of hormone therapy with drospirenone-estradiol on endometrioid type endometrial cancer patients
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Lim S, Kim YH, Lee KB, Lee JM
- KMID: 2417455
- J Gynecol Oncol.
- 2018 Sep;29(5):e72.
- doi: 10.3802/jgo.2018.29.e72
OBJECTIVE: To determine whether drospirenone/estradiol (DRSP/E2) has an adverse effect on clinical outcomes in surgically staged International Federation of Gynecology and Obstetrics (FIGO) stage I/II endometrial cancer (EC) patients. METHODS: In... -
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- Dental Panoramic Radiographic Indices as a Predictor of Osteoporosis in Postmenopausal Saudi Women
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Balto KA, Gomaa MM, Feteih RM, AlAmoudi N, Elsamanoudy AZ, Hassanien , Ardawi MS
- KMID: 2419844
- J Bone Metab.
- 2018 Aug;25(3):165-173.
- doi: 10.11005/jbm.2018.25.3.165
BACKGROUND: Many oral presentations of osteoporosis-a bone metabolic disease-were recorded. Thus, we aimed to assess panoramic radiomorphometric indices with bone mineral density (BMD) values among Saudi postmenopausal women and its... -
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- Porcine intestinal lymphoid tissues synthesize estradiol
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Park CJ, Kim H, Jin J, Barakat R, Lin PC, Choi JM, Ko CJ
- KMID: 2417561
- J Vet Sci.
- 2018 Jul;19(4):477-482.
- doi: 10.4142/jvs.2018.19.4.477
Estradiol (17β-estradiol) is synthesized primarily in the gonads of both sexes and regulates the development and function of reproductive organs. Recently, we reported that intestinal lymphocyte homeostasis is regulated by... -
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- Delayed puberty versus hypogonadism: a challenge for the pediatrician
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Bozzola M, Bozzola E, Montalbano C, Stamati FA, Ferrara P, Villani A
- KMID: 2417760
- Ann Pediatr Endocrinol Metab.
- 2018 Jun;23(2):57-61.
- doi: 10.6065/apem.2018.23.2.57
Constitutional delay of growth and puberty (CDGP) is the most common cause of delayed puberty (DP), is mainly found in males, and is characterized by short stature and delayed skeletal... -
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