J Korean Med Sci.  2006 Apr;21(2):300-303. 10.3346/jkms.2006.21.2.300.

Clinical Efficacy of Body Mass Index as Predictor of In Vitro Fertilization and Embryo Transfer Outcomes

• Ku SY
• Kim SD
• Jee BC
• Suh CS
• Choi YM
• Kim JG
• Moon SY
• Kim SH

• KMID: 1781839
• DOI: http://doi.org/10.3346/jkms.2006.21.2.300

Abstract

The aim of this study was to evaluate the clinical efficacy of body mass index (BMI) as a predictor of in vitro fertilization and embryo transfer (IVF-ET) outcomes. Two hundred twenty-three IVF-ET cycles in 164 patients under 37 yr using GnRH agonist long protocols were included in this retrospective study. All of the selected cases were divided into two groups by a cutoff of 24 kg/m2 and these two groups were compared in regard to the outcomes of IVF-ET. There were no significant differences between group 1 (BMI <24 kg/m2) and group 2 (BMI > or = 24 kg/m2) in age, basal serum FSH level, estradiol (E2) level and endometrial thickness on hCG day, number of retrieved oocytes and transferred embryos. However, higher doses of gonadotropins were used in group 2 (30.8+/-12.7 ampoules vs. 35.4+/-15.3 ampoules, p=0.051). The clinical pregnancy rate was significantly lower in group 2 (25.9% vs. 10.5%, p=0.041) and implantation rate tended to be lower in group 2 (12.7% vs. 6.8%, p=0.085). BMI > or = 24 kg/m2 can be a candidate prognosticator of IVF-ET outcomes.

Keyword

Body Mass Index; Fertilization; In Vitro; Embryo Transfer; Reproductive Techniques; Assited

MeSH Terms

Treatment Outcome
Prognosis
Pregnancy
Obesity/complications/pathology
Infertility, Female/complications/pathology/therapy
Humans
*Fertilization in Vitro
Female
*Embryo Transfer
Embryo Implantation
*Body Mass Index
Adult

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