Korean J Obstet Gynecol.  2005 Jul;48(7):1816-1819.

Fibroadenoma of the Vulva: A Case Report

Affiliations
  • 1Department of Obstetrics and Gynecology, College of Medicine, University of Wonkwang Medical School, Iksan, Korea.
  • 2Department of Pathology and Institute of Wonkwang Medical Science, College of Medicine, University of Wonkwang Medical School, Iksan, Korea. hbmoon@wonkwang.ac.kr
  • 3Department of Pathology, Gunsan Medical Center of Wonkwang University Hospital, Gunsan, Korea.

Abstract

Fibroadenoma is a rare lesion of the vulva. It has been proposed that the origin of the tissue is either ectopic breast tissue or vulvar mammary-like glands (MLG). We report a case of vulvar fibroadenoma in a 33-year-old woman with a right vulvar mass presenting clinically as vulvar cyst. The cut surface of the tumor showed a white and homogenous appearance that was 2.5 cm in maximum dimension. Microscopically, the lesion was well-circumscribed but non-encapsulated. It revealed nodular, glandular and stromal proliferation, consistent with fibroadenoma of breast. Immunohistochemical staining for the estrogen receptor and progesteron receptor revealed nuclear positivity in the epithelium. Smooth muscle actin confirmed the presence of a myoepithelial cell layer. Staining for pancytokeratin showed epithelial cytoplasmic positivity.

Keyword

Vulva; Fibroadenoma; Ectopic breast tissue; Mammary-like glands

MeSH Terms

Actins
Adult
Breast
Cytoplasm
Epithelium
Estrogens
Female
Fibroadenoma*
Humans
Muscle, Smooth
Vulva*
Actins
Estrogens
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