Korean J Obstet Gynecol.  2004 Dec;47(12):2499-2505.

Two Cases of Uterine Papillary Serous Carcinoma

Affiliations
  • 1Department of Obstetrics and Gynecology, Daegu Fatima Hospital, Daegu, Korea.
  • 2Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.

Abstract

Uterine papillary serous carcinoma (UPSC) behave more aggressively than other endometrial carcinomas and have a propensity for intraabdominal spread, simulating the behavior of ovarian carcinoma. Because of high relapsing rate, and high mortality rate of UPSC, many gynecologist studied about its treatment regimen and recommended many treatment method. Many investigators recommended that patients with UPSC should undergo a staging laparotomy and they suggested the surgery should include at least total hysterectomy, bilateral salpingo-oophorectomy, omentectomy, pelvic lymphadenectomy, paraaortic lymphadenectomy, peritoneal washing and peritoneal cytology, By and large, adjuvant systemic Platinum based chemotherapy or, paclitaxel based chemotherapy and adjuvant whole abdominal irradiation or pelvic irradiation was prescribed. We experienced two cases of the UPSC stage IIIc and stage IV diagnosed after explolaparotomy. We present these cases and review the literatures about the optimal treatment regimen of UPSC.

Keyword

UPSC; Laparotomy; Chemotherapy; Irradiation

MeSH Terms

Drug Therapy
Endometrial Neoplasms
Female
Humans
Hysterectomy
Laparotomy
Lymph Node Excision
Mortality
Paclitaxel
Platinum
Research Personnel
Paclitaxel
Platinum
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