Korean J Obstet Gynecol.  2004 Feb;47(2):405-408.

A Case of Caudal Regression Syndrome in the Newborn of the Diabetic Mother

Affiliations
  • 1Department of Obstetrics and Gynecology, College of Medicine, Catholic University, Seoul, Korea.

Abstract

The Caudal regression syndrome is characterized by sacrococcygeal or lumbosacrococcygeal agenesis, of variable extent, most often accompanied by multiple musculoskeletal abnormalities of the pelvis and legs. It is rare fetal complication of diabetic pregnancy. Although the exact teratogenic mechanism is not known, hyperglycemia appears to play a crucial role as a teratogen. Strict control of diabetes preconceptually and in early pregnancy is presumed to reduce the risk of occurrence. We report a case of caudal regression syndrome detected by pelvic radiography and MRI in the newborn of the diabetic mother.

Keyword

Caudal regression syndrome; Diabetes

MeSH Terms

Humans
Hyperglycemia
Infant, Newborn*
Leg
Magnetic Resonance Imaging
Mothers*
Musculoskeletal Abnormalities
Pelvis
Pregnancy
Radiography
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