Korean J Obstet Gynecol.
2005 Jul;48(7):1788-1792.
A Case of Caudal Regression Syndrome Diagnosed by Prenatal Ultrasonography
- Affiliations
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- 1Department of Obstetrics and Gynecology, Gachon Medical School, Incheon, Korea. hwangbyc@ghil.com
Abstract
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Caudal regression syndrome is rare malformative syndrome characterized by lower vertebral agenesis, accompanied by abnormalities of the pelvis, lower extremities and urogenital malformation. Although the cause is not clear, hyperglycemia during the organogenesis may be important teratogen. Strict evaluation of diabetes and its control in preconception and early pregnancy are important to prevent this malformation. And ultrasonography in the first trimester should be recommended for early detection of this syndrome. We report a case of caudal regression syndrome detected by prenatal ultrasonography of the gestational diabetic mother.