J Korean Soc Neonatol.  2009 May;16(1):89-93.

Multiple Congenital Anomalies in a Neonate of a Diabetic Mother

Affiliations
  • 1Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea. neopark@hanyang.ac.kr
  • 2Department of Radiology, College of Medicine, Hanyang University, Seoul, Korea.

Abstract

Maternal diabetes is known to have teratogenic effects which increase the risk for congenital anomalies, such as caudal dysplasia, cardiac defects, hydronephrosis, and small left colon syndrome. Infants of diabetic mothers have a 10-fold higher frequency of anomalies in the central nervous system and a 5-fold higher frequency of congenital heart defects. However, jejunal atresia combined with multiple anomalies of the face, ears, and hands has rarely been reported. Herein we report a neonate born to a diabetic mother, who had hemifacial microsomia, displacement of the lacrimal ducts, polydactyly of the right hand, microtia of the right ear and proximal jejunal atresia presenting as bile regurgitation on the 1st day of life.

Keyword

Gestational diabetes; Congenital anomalies; Jejunal atresia; Hemifacial microsomia; Polydactyly; Microtia

MeSH Terms

Bile
Central Nervous System
Colon
Congenital Abnormalities
Diabetes, Gestational
Displacement (Psychology)
Ear
Facial Asymmetry
Female
Hand
Heart Defects, Congenital
Humans
Hydronephrosis
Infant
Infant, Newborn
Intestinal Atresia
Mothers
Polydactyly
Pregnancy
Congenital Abnormalities
Ear
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