Korean J Obstet Gynecol.
2003 Jun;46(6):1135-1139.
Hysteroscopic Endometrial Ablation as a Treatment of Abnormal Uterine Bleeding in Renal Transplant Patients
- Affiliations
-
- 1Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.
- 2Department of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.
Abstract
OBJECTIVE
To assess the effectiveness and safety of hysteroscopic endometrial ablation as a surgical management of abnormal uterine bleeding developed in renal transplant patients.
METHODS
Data were collected retrospectively from 62 patients referred to Department of Obstetrics and Gynecology, Yonsei University Medical Center from January 1999 to December 2001 for abnormal uterine bleeding with prior history of renal transplantation who subsequently received hysteroscopic endometrial ablation. Hormonal status of these patients were evaluated before the operation by sampling estradiol (E2), lutenizing hormone (LH), follicle-stimulating hormone (FSH), thyroid stimulating hormone (TSH), and prolactin. Mean follow-up duration was 6 months. Levonorgestrel-releasing intrauterine system (LNG-IUS)s were inserted in those who experienced recurrent bleeding.
RESULTS
Mean age of patients was 34.6+/-6.7 years and mean duration from renal transplant to onset of abnormal uterine bleeding was 4.5+/-2.5 years. All hormone levels (E2, LH, FSH, TSH, prolactin) were within normal range. 54 out of 62 patients (87.0%) who underwent hysteroscopic endometrial ablation reported decreased bleeding: amenorrhea in 25 (40.3%), spotting in 19 (30.6%), and eumenorrhea in 10 (16.1%). None reported complications related to the procedure. LNG-IUSs were inserted into 8 patients who experienced continuous bleeding, 5 out of whom showed symptomatic improvement: spotting in 3 (4.9%) and eumenorrhea in 2 (3.2%). 3 patients in whom LNG-IUS had no effect received total abdominal hysterectomy.
CONCLUSION
Hysteroscopic endometrial ablation as a surgical management of abnormal uterine bleeding developed in renal transplant patients is an effective and safe procedure.
MeSH Terms
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Academic Medical Centers
Amenorrhea
Endometrial Ablation Techniques*
Estradiol
Female
Follicle Stimulating Hormone
Follow-Up Studies
Gynecology
Hemorrhage
Humans
Hysterectomy
Kidney Transplantation
Metrorrhagia
Obstetrics
Prolactin
Reference Values
Retrospective Studies
Thyrotropin
Uterine Hemorrhage*
Estradiol
Follicle Stimulating Hormone
Prolactin
Thyrotropin
