Korean J Obstet Gynecol.
2003 Apr;46(4):834-837.
A Case of Primary Endometrial Squamous Cell Carcinoma
- Affiliations
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- 1Department of Obstetrics and Gynecology, College of Medicine, Sungkyunkwan University, Samsung Medical Center, Seoul, Korea.
- 2Department of Anatomical Pathology, College of Medicine, Sungkyunkwan University, Samsung Medical Center, Seoul, Korea.
Abstract
- Primary squamous cell carcinoma of the endometrium is very rare. In 1928 Flumann suggested three criteria for diagnosis: (1) no coexisting endometrial adenocarcinoma, (2) no connection between the endometrial squamous cell carcinoma and squamous epithelium of the cervix, and (3) no cervical squamous cell carcinoma. In 1975, the World Health Organization (WHO) updated Flumann's criteria by adding that the tumor must contain clear evidence of squamous differentiation, such as the presence of intercellular bridges and/or keratin. Most patients with endometrial squmamous cell carcinoma have had poor prognosis regardless of their stages of disease or treatment. In this report we present the clinical and pathological findings of a case of a primary squamous cell carcinoma that developed in the endometrial cavity of a 65-year-old patient with a review of the concerned literatures.
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