Korean J Obstet Gynecol.  2003 Apr;46(4):746-751.

Umbilical Nucleated Red Blood Cell Counts and Perinatal Outcome According to Doppler End-Diastolic Velocity in Severe Preeclampsia

• Oh JH
• Lim YK
• Lee HJ
• Kim HS
• Yang JI
• Ryu HS
• Oh KS

Abstract

OBJECTIVE
To assess the umbilical nucleated red blood cell counts and perinatal outcomes according to umbilical artery Doppler end diastolic velocity in severe preeclampsia.
MATERIALS AND METHODS
A prospective case-control study comparing 42 severe preeclampsia patients who had present umbilical artery end diastolic velocity with 7 severe preeclampsia patients who absent end diastolic velocity for umbilical nucleated red blood cell counts and perinatal outcomes.
RESULTS
Those with absent end diastolic velocity did not have significantly greater nucleated red blood cell counts, but they had increased hemoglobin, hematocrit. These newborn had significantly lower birth weight, increased Cesarean section rate for fetal distress and been more frequently admitted to the neonatal intensive care unit. These newborn also had significantly increased intracranial hemorrhage,assisted ventilation and longer hospital days.
CONCLUSION
No correlation with nucleated red blood cell counts and chronic fetal hypoxia were presented. However further study with more expanded cases for the role of nucleated red blood cell counts as a marker of fetal hypoxia will be needed.

Keyword

Nucleated red blood cell counts; Doppler end diastolic velocity; Preeclampsia

MeSH Terms

Birth Weight
Case-Control Studies
Cesarean Section
Erythrocyte Count*
Erythrocytes*
Female
Fetal Distress
Fetal Hypoxia
Hematocrit
Humans
Infant, Newborn
Intensive Care, Neonatal
Pre-Eclampsia*
Pregnancy
Prospective Studies
Umbilical Arteries
Ventilation