Korean J Nutr.
2003 Dec;36(10):1030-1035.
Evaluation of Nutritional Safety for the Herbicide-Resistant Rice in Growing Male Rats
- Affiliations
-
- 1Agriproduct Science Division, National Rural Living Science Institute, NIAST, RDA, Suwon, Korea.
- 2Plant Biotechnology Division, National Institute of Agricultural Biotechnology, RDA, Suwon, Korea.
- 3Pesticide Safety Division, Crop Protection, NIAST, RDA, Suwon, Korea.
- 4Food Microbiology Division, Food Evaluation Department, Korea Food and Drug Administration, Seoul, Korea.
Abstract
- This study was conducted to evaluate the safety of herbicide-resistant rice, a genetically modified organism (GMO) developed by the Rural Development Administration, in Sprague-Dawley rats. The nutrient content of herbicide-resistant polished and brown cooked rice was compared with that of conventional Ilpum polished and brown cooked rice to assess composition equivalence. Compositional analysis was performed to measure proximates, fiber, and minerals before animal feeding. Growing male rats were fed one of the following four diets for six weeks: Ilpum polished cooked rice (IP) and Ilpum brown cooked rice (IB) as a non-GMO and herbicide-resistant polished cooked rice (GP) and brown cooked rice (GB) as a GMO. We checked clinical symptoms (anorexia, salivation, diarrhea, polyuria, anuria, fecal change) every day, food intake, change of body weight twice a week, and serum biochemistry and organ weights after 6 weeks of experimental feeding among the four groups. Nutrient content of the herbicide-resistant rice was similar to that of the non-transgenic control and was within the published range observed for non-transgenic rice. We could not find any significant difference in the above-mentioned items as the index to be checked in the animals fed the GMO. These results suggest that the nutrient content of genetically modified herbicide-resistant rice is compositionally equivalent to that of conventional Ilpum rice and that growing male rats fed herbicide-resistant rice are no different from those fed Ilpum rice, non-GMO for 6 weeks.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Effect of retrograded rice on weight control, gut function, and lipid concentrations in rats
- Assessment of early nutritional state in critical patients with intoxication and the effect of nutritional status on prognosis
- A Case of Rice Allergy Caused by Thin Rice Porridge during the Weaning Period
- The Impact of Kinds of Dietary Grain and Dietary Lipid Level on the Glucose Metabolism and Antithrombogenic Capacity of Full Grown Obesity Induced Rats
- Effect of Age on Glucose Metabolism of Skeletal Muscle in Rats
