Korean J Med.
2014 Nov;87(5):609-614. 10.3904/kjm.2014.87.5.609.
A Case of Crescentic Glomerulonephritis and Marginal Zone B-cell Lymphoma
- Affiliations
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- 1Department of Internal Medicine, Seoul National University, Boramae Medical Center, Seoul, Korea. yoonkyu@snu.ac.kr
- 2Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
- 3Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
- KMID: 2269205
- DOI: http://doi.org/10.3904/kjm.2014.87.5.609
Abstract
- Secondary rapidly progressive glomerulonephritis (RPGN) can be caused by many diseases and conditions, including vasculitis, systemic rheumatic diseases, infections, drugs and malignancies. Among the secondary RPGNs, malignancy-associated RPGN is extremely rare and causes renal function deterioration within several weeks to months. Thus, timely immunosuppressant therapy can improve renal outcome. Herein, we describe a case of RPGN detected simultaneously with marginal zone B-cell lymphoma. An 82-year-old male patient, who presented generalized edema and oliguria, was diagnosed with crescentic glomerulonephritis and marginal B-cell lymphoma. After the patient was given methylprednisolone pulse therapy, renal function was restored and hemodialysis was successfully discontinued without complications.
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